E-ISSN 2231-3206 | ISSN 2320-4672
 

Educational Strategies

Online Publishing Date:
18 / 01 / 2015

 


Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model

Ashishkumar Zala, ND Kantharia, Aashal B Shah.


Abstract
To simplify the principles of pharmacokinetics single compartment model is designed with certain assumptions. Objectives of this model are to understand basic principles of pharmacokinetics, to represent graphically the typical natural log concentration versus time curve for single compartment model after (intravenous) dose and to understand how to calculate elimination half-life using graphical log-concentration versus time as well as by mathematical method.

Key words: Pharmacokinetic, Clearance, Volume of distribution, Half life ,Optical density, area under curve (AUC)


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ashishkumar Zala
Articles by ND Kantharia
Articles by Aashal B Shah
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah. Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model. Natl J Physiol Pharm Pharmacol. 2015; 5(1): 76-78. doi:10.5455/njppp.2015.5.010820143


Web Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah. Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model. https://www.njppp.com/?mno=162020 [Access: March 15, 2024]. doi:10.5455/njppp.2015.5.010820143


AMA (American Medical Association) Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah. Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model. Natl J Physiol Pharm Pharmacol. 2015; 5(1): 76-78. doi:10.5455/njppp.2015.5.010820143



Vancouver/ICMJE Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah. Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model. Natl J Physiol Pharm Pharmacol. (2015), [cited March 15, 2024]; 5(1): 76-78. doi:10.5455/njppp.2015.5.010820143



Harvard Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah (2015) Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model. Natl J Physiol Pharm Pharmacol, 5 (1), 76-78. doi:10.5455/njppp.2015.5.010820143



Turabian Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah. 2015. Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model. National Journal of Physiology, Pharmacy and Pharmacology, 5 (1), 76-78. doi:10.5455/njppp.2015.5.010820143



Chicago Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah. "Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model." National Journal of Physiology, Pharmacy and Pharmacology 5 (2015), 76-78. doi:10.5455/njppp.2015.5.010820143



MLA (The Modern Language Association) Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah. "Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model." National Journal of Physiology, Pharmacy and Pharmacology 5.1 (2015), 76-78. Print. doi:10.5455/njppp.2015.5.010820143



APA (American Psychological Association) Style

Ashishkumar Zala, ND Kantharia, Aashal B Shah (2015) Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model. National Journal of Physiology, Pharmacy and Pharmacology, 5 (1), 76-78. doi:10.5455/njppp.2015.5.010820143