E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Correlation of bleeding time and clotting time in different phases of menstrual cycle

Shivani Prajapati, Ritu Adhana, Anjali Verma.

Abstract
Background: Changes in the levels of female sex hormones during the menstrual cycle are known to affect the coagulation cascade by producing parallel changes in the prothrombotic tendency and the fibrinolytic activity of healthy women.

Aims and Objectives: The aims of the study was to access the changes in bleeding time (BT) and clotting time (CT) during different phases of menstruation.

Materials and Methods: Study was conducted in the Department of Physiology, TMMC and RC over a period of 1 year. A group of 40 females between the age group of 18–25 years having normal menstrual cycle were selected. Females with hormonal disorders, taking hormonal medication having hematological, gynecological or any chronic disorder were excluded. There BT and CT were accessed in four phases of menstrual cycle, i.e., menstrual phase, proliferative phase, ovulatory phase, and secretory phase. Data were analyzed using SPSS software.

Results: The mean BT shows a significant difference (P = 0.001). BT was least around the Ovulatory Phase or mid-cycle, and it increases during secretory phase. CT was least around ovulatory or mid-cycle, and it increases during secretory phase. However, the difference of CT in different phases was not statistically significant.

Conclusion: The present study indicates that primary and secondary hemostatic mechanism activities are higher in the follicular and ovulatory phase than remaining phases. Hence, optimal hemostatic testing time must be done in menstrual and early follicular phase.

Key words: Bleeding Time; Clotting Time; Menstrual Phase; Ovulatory Phase; Proliferative Phase; Secretory Phase


 
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Pubmed Style

Shivani Prajapati| Ritu Adhana| Anjali Verma. Correlation of bleeding time and clotting time in different phases of menstrual cycle. doi:10.5455/njppp.2018.8.0619707062018


Web Style

Shivani Prajapati| Ritu Adhana| Anjali Verma. Correlation of bleeding time and clotting time in different phases of menstrual cycle. http://www.njppp.com/?mno=300892 [Access: September 19, 2018]. doi:10.5455/njppp.2018.8.0619707062018


AMA (American Medical Association) Style

Shivani Prajapati| Ritu Adhana| Anjali Verma. Correlation of bleeding time and clotting time in different phases of menstrual cycle. doi:10.5455/njppp.2018.8.0619707062018



Vancouver/ICMJE Style

Shivani Prajapati| Ritu Adhana| Anjali Verma. Correlation of bleeding time and clotting time in different phases of menstrual cycle. doi:10.5455/njppp.2018.8.0619707062018



Harvard Style

Shivani Prajapati| Ritu Adhana| Anjali Verma (2018) Correlation of bleeding time and clotting time in different phases of menstrual cycle. doi:10.5455/njppp.2018.8.0619707062018



Turabian Style

Shivani Prajapati| Ritu Adhana| Anjali Verma. 2018. Correlation of bleeding time and clotting time in different phases of menstrual cycle. doi:10.5455/njppp.2018.8.0619707062018



Chicago Style

Shivani Prajapati| Ritu Adhana| Anjali Verma. "Correlation of bleeding time and clotting time in different phases of menstrual cycle." doi:10.5455/njppp.2018.8.0619707062018



MLA (The Modern Language Association) Style

Shivani Prajapati| Ritu Adhana| Anjali Verma. "Correlation of bleeding time and clotting time in different phases of menstrual cycle." doi:10.5455/njppp.2018.8.0619707062018



APA (American Psychological Association) Style

Shivani Prajapati| Ritu Adhana| Anjali Verma (2018) Correlation of bleeding time and clotting time in different phases of menstrual cycle. doi:10.5455/njppp.2018.8.0619707062018





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