E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Neurological manifestation of HIV infection in North-Eastern part of India

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena.

Cited by (2)

Abstract
Background: The nervous system is among the most frequent and serious target of HIV infection, occurring in patients with profound immunosuppression even some time neurological disease is the first manifestation of symptomatic HIV infection in 10–20% of patients.

Aims & Objective: (1) To study the clinical, investigation profile and various neurological disorders in HIV positive patients; (2) To correlate neurological manifestations in HIV patients with CD4 Counts.
Materials and Methods: 40 HIV positive patients with neurological manifestations were enrolled. Apart from routine investigations, CD4 cell count, MRI brain, CSF, electromyography and nerve conduction study were done whereas required.

Results: Meningitis was the commonest diagnosis (52.5%) followed Peripheral neuropathy (20%). Cerebrovascular accident was present in 3 cases. Intracranial space occupying lesion was found in 3 cases. Headache was the commonest neurological symptom seen in 25(62.5%) patients. Altered sensorium was found in 55%. Cranial nerve involvement was seen in 7 (17.5%) patients. Convulsion was reported in 10 (25 %) of the patients. Choreoathetoid movement was present in one patient. CD4 Count was done in 37 patients. In 13 patients it was between 200-500/μl & <200/μl in 24 Patients. CD4 count was <200/ μl in most of the patients having TBM (73%), < 200/ μl in 75% of cryptococcal meningitis.

Conclusion: Most of the neurological sign symptoms are due to secondary causes which vary according to the geographical areas. So the knowledge of epidemiology of neurological presentation may help in early diagnosis and treatment of patients.

Key words: Neurologic manifestation, HIV, India


 
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This Article Cited By the following articles


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How to Cite this Article
Pubmed Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena. Neurological manifestation of HIV infection in North-Eastern part of India. Natl J Physiol Pharm Pharmacol. 2014; 4(1): 4-8. doi:10.5455/njppp.2014.4.130620131


Web Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena. Neurological manifestation of HIV infection in North-Eastern part of India. https://www.njppp.com/?mno=35024 [Access: June 01, 2022]. doi:10.5455/njppp.2014.4.130620131


AMA (American Medical Association) Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena. Neurological manifestation of HIV infection in North-Eastern part of India. Natl J Physiol Pharm Pharmacol. 2014; 4(1): 4-8. doi:10.5455/njppp.2014.4.130620131



Vancouver/ICMJE Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena. Neurological manifestation of HIV infection in North-Eastern part of India. Natl J Physiol Pharm Pharmacol. (2014), [cited June 01, 2022]; 4(1): 4-8. doi:10.5455/njppp.2014.4.130620131



Harvard Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena (2014) Neurological manifestation of HIV infection in North-Eastern part of India. Natl J Physiol Pharm Pharmacol, 4 (1), 4-8. doi:10.5455/njppp.2014.4.130620131



Turabian Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena. 2014. Neurological manifestation of HIV infection in North-Eastern part of India. National Journal of Physiology, Pharmacy and Pharmacology, 4 (1), 4-8. doi:10.5455/njppp.2014.4.130620131



Chicago Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena. "Neurological manifestation of HIV infection in North-Eastern part of India." National Journal of Physiology, Pharmacy and Pharmacology 4 (2014), 4-8. doi:10.5455/njppp.2014.4.130620131



MLA (The Modern Language Association) Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena. "Neurological manifestation of HIV infection in North-Eastern part of India." National Journal of Physiology, Pharmacy and Pharmacology 4.1 (2014), 4-8. Print. doi:10.5455/njppp.2014.4.130620131



APA (American Psychological Association) Style

S K Sharma, N C Dwivedi, Nilesh Kumar, Anju Bharti, L P Meena (2014) Neurological manifestation of HIV infection in North-Eastern part of India. National Journal of Physiology, Pharmacy and Pharmacology, 4 (1), 4-8. doi:10.5455/njppp.2014.4.130620131