E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Comparison of oxidative stress between premenopausal and postmenopausal women

Josephine Vincent, Jiji Inassi.

Abstract
Background: Menopause is a natural biological phenomenon during which irreversible changes in the hormonal and reproductive functions of the ovaries lead to physical, social, and psychological changes in women. The progressive loss of estrogen and its protective effects predisposes to the development of oxidative stress and related diseases in postmenopausal women which, in turn, can impair their quality of life.

Aims and Objectives: This study aims to study and compare the levels of serum malondialdehyde (MDA) and superoxide dismutase (SOD) in premenopausal and postmenopausal females.

Materials and Methods: A cross-sectional comparative study was conducted in 100 healthy women, of which 50 were postmenopausal in the age group of 50–60 years and 50 were premenopausal in the age group of 30–40 years. The data were analyzed using Statistical Package for the Social Sciences version 18.

Results: Oxidative stress was increased in postmenopausal women as evidenced by significantly elevated MDA and reduced SOD.

Conclusion: Menopause is associated with oxidative stress which predisposes to the development of cardiovascular diseases, vasomotor disturbances, osteoporosis, depression, diabetes, and hypertension. Dietary management, antioxidant supplementation, and moderate physical activity would help them to prevent diseases related to menopause.

Key words: Menopause; Oxidative Stress; Osteoporosis; Cardiovascular Diseases


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Josephine Vincent
Articles by Jiji Inassi
on Google
on Google Scholar
Article Statistics
 Viewed: 1
Downloaded: 12


How to Cite this Article
Pubmed Style

Vincent J, Inassi J. Comparison of oxidative stress between premenopausal and postmenopausal women. doi:10.5455/njppp.2020.10.02051202002032020


Web Style

Vincent J, Inassi J. Comparison of oxidative stress between premenopausal and postmenopausal women. http://www.njppp.com/?mno=88196 [Access: March 13, 2020]. doi:10.5455/njppp.2020.10.02051202002032020


AMA (American Medical Association) Style

Vincent J, Inassi J. Comparison of oxidative stress between premenopausal and postmenopausal women. doi:10.5455/njppp.2020.10.02051202002032020



Vancouver/ICMJE Style

Vincent J, Inassi J. Comparison of oxidative stress between premenopausal and postmenopausal women. doi:10.5455/njppp.2020.10.02051202002032020



Harvard Style

Vincent, J. & Inassi, . J. (2020) Comparison of oxidative stress between premenopausal and postmenopausal women. doi:10.5455/njppp.2020.10.02051202002032020



Turabian Style

Vincent, Josephine, and Jiji Inassi. 2020. Comparison of oxidative stress between premenopausal and postmenopausal women. doi:10.5455/njppp.2020.10.02051202002032020



Chicago Style

Vincent, Josephine, and Jiji Inassi. "Comparison of oxidative stress between premenopausal and postmenopausal women." doi:10.5455/njppp.2020.10.02051202002032020



MLA (The Modern Language Association) Style

Vincent, Josephine, and Jiji Inassi. "Comparison of oxidative stress between premenopausal and postmenopausal women." doi:10.5455/njppp.2020.10.02051202002032020



APA (American Psychological Association) Style

Vincent, J. & Inassi, . J. (2020) Comparison of oxidative stress between premenopausal and postmenopausal women. doi:10.5455/njppp.2020.10.02051202002032020





Most Viewed Articles
  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114

  • Most Downloaded
  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Evaluation of potential drug-drug interaction in indoor patients of pediatric department of tertiary care hospital
    Simran Patel, Mayur Chaudhari, Nrupal Patel
    Natl J Physiol Pharm Pharmacol. 2019; 9(10): 1012-1016
    » Abstract » doi: 10.5455/njppp.2019.9.0725209072019

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract & References » doi: 10.5455/njppp.2011.1.1-8

  • Most Cited Articles
  • Promoting active learning in respiratory physiology – Positive student perception and improved outcomes
    Richa Thaman, Sukhjinder Dhillon, Sanjeev Saggar, Meenakshi Gupta, Harkirat Kaur
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 27-34
    » Abstract & References » doi: 10.5455/njppp.2013.3.27000
    Cited : 11 times [Click to see citing articles]

  • Pattern of mobile phone usage and its effects on psychological health, sleep, and academic performance in students of a medical university
    Naveenta Gupta, Sonia Garg, Khushdeep Arora
    Natl J Physiol Pharm Pharmacol. 2016; 6(2): 132-139
    » Abstract & References » doi: 10.5455/njppp.2016.6.0311201599
    Cited : 11 times [Click to see citing articles]

  • Quercetin improved spatial memory dysfunctions in rat model of intracerebroventricular streptozotocin-induced sporadic Alzheimer’s disease
    Manouchehr Ashrafpour, Sahar Parsaei, Hamid Sepehri
    Natl J Physiol Pharm Pharmacol. 2015; 5(5): 411-415
    » Abstract & References » doi: 10.5455/njppp.2015.5.2308201563
    Cited : 11 times [Click to see citing articles]

  • A study of oxidative stress in gentamicin induced nephrotoxicity and effect of antioxidant vitamin C in Wistar rats.
    Chetankumar R. Acharya, Hetal N. Thakar, S. K. Vajpeyee
    Natl J Physiol Pharm Pharmacol. 2013; 3(1): 14-20
    » Abstract & References » doi: 10.5455/njppp.2013.3.14-20
    Cited : 10 times [Click to see citing articles]

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract & References » doi: 10.5455/njppp.2013.3.109-114
    Cited : 7 times [Click to see citing articles]