E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats

Neeraja Rani Guruvu, Venkatanarayana Narapogu, D Lakshmi Lalitha, Bandaru Narasinga Rao Bandaru, Sai Sailesh Kumar Goothy, D Murali Mohan Rao.

Abstract
Background: Silver nanoparticles (AgNPs) show ample antibacterial activities when combining with honey.

Aim and Objective: The study was designed to determine the antibacterial activity of different kinds of honey against the common wound pathogen Staphylococcus aureus.

Materials and Methods: Bacterial strain was used to inoculate the wound. S. aureus ATCC-25923 was used in the study.

Results: Wound infection examination was done by total count of bacterial load. In all three groups, better percentage of the wound closer, histological, blood, and tissue parameters identified in honey combine with AgNPs, showed a synergistic effect.

Conclusion: Honey and AgNPs showed synergistic effect. It is recommended to apply both the products together.

Key words: Honey; Silver Nanoparticles; Staphylococcus aureus; Blood and Tissue Parameters


 
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How to Cite this Article
Pubmed Style

Guruvu NR, Narapogu V, Lalitha DL, Bandaru BNR, Goothy SSK, Rao DMM. Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats. doi:10.5455/njppp.2022.11.07239202120072021


Web Style

Guruvu NR, Narapogu V, Lalitha DL, Bandaru BNR, Goothy SSK, Rao DMM. Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats. http://www.njppp.com/?mno=95780 [Access: September 03, 2021]. doi:10.5455/njppp.2022.11.07239202120072021


AMA (American Medical Association) Style

Guruvu NR, Narapogu V, Lalitha DL, Bandaru BNR, Goothy SSK, Rao DMM. Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats. doi:10.5455/njppp.2022.11.07239202120072021



Vancouver/ICMJE Style

Guruvu NR, Narapogu V, Lalitha DL, Bandaru BNR, Goothy SSK, Rao DMM. Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats. doi:10.5455/njppp.2022.11.07239202120072021



Harvard Style

Guruvu, N. R., Narapogu, . V., Lalitha, . D. L., Bandaru, . B. N. R., Goothy, . S. S. K. & Rao, . D. M. M. (2022) Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats. doi:10.5455/njppp.2022.11.07239202120072021



Turabian Style

Guruvu, Neeraja Rani, Venkatanarayana Narapogu, D Lakshmi Lalitha, Bandaru Narasinga Rao Bandaru, Sai Sailesh Kumar Goothy, and D Murali Mohan Rao. 2022. Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats. doi:10.5455/njppp.2022.11.07239202120072021



Chicago Style

Guruvu, Neeraja Rani, Venkatanarayana Narapogu, D Lakshmi Lalitha, Bandaru Narasinga Rao Bandaru, Sai Sailesh Kumar Goothy, and D Murali Mohan Rao. "Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats." doi:10.5455/njppp.2022.11.07239202120072021



MLA (The Modern Language Association) Style

Guruvu, Neeraja Rani, Venkatanarayana Narapogu, D Lakshmi Lalitha, Bandaru Narasinga Rao Bandaru, Sai Sailesh Kumar Goothy, and D Murali Mohan Rao. "Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats." doi:10.5455/njppp.2022.11.07239202120072021



APA (American Psychological Association) Style

Guruvu, N. R., Narapogu, . V., Lalitha, . D. L., Bandaru, . B. N. R., Goothy, . S. S. K. & Rao, . D. M. M. (2022) Synergistic antimicrobial activity of honey combined with silver nanoparticles topically applied in experimentally infected wounds in Wistar albino rats. doi:10.5455/njppp.2022.11.07239202120072021