Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions

Rajesh Paluru; Yoganandareddy Indla; Ramaswamy Chellam; Rajani Santhakumari

doi:10.5455/njppp.2016.6.0411404052016

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Online Publishing Date:
31 / 08 / 2016

Natl J Physiol Pharm Pharmacol. 2016; 6(5): 412-415

doi: 10.5455/njppp.2016.6.0411404052016

Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari.

Abstract
Background: Outer hair cells in the organ of Corti are not directly involved in deciding the threshold of the acoustic stimulus, but their damage will increase the hearing threshold and may even cause the neuronal deafness. Type 2 diabetes is increasing globally at an alarming rate; one of many complications of Type 2 diabetes is loss of hearing. In Type 2 diabetes, poor glycemic status is the cause for neuropathy or microangiopathy which may affect the normal hearing.

Aims and Objectives: To observe the effect of Type 2 diabetes on the functional status of outer hair cells. To illustrate the effect of Type 2 diabetes on outer hair cells for right and left ear is same or different.

Materials and Methods: A total of 50 Type 2 diabetic subjects, aged between 30 to 55 years, both sexes were included as test group after assessing their glycemic index. 50 age and sex matched healthy individuals are also included as control group. Functioning of outer hair cells was assessed with distortion product otoacoustic emissions (DPOAEs).

Results: Glycosylated hemoglobin percentage among test (8.58 ± 0.83) and control group subjects (5.28 ± 0.50) is statistically significant (<0.0001). Odds of failing the DPOAEs are 7 and 15 times higher in patients with Type 2 diabetes than those without diabetes for right and left ear, respectively.

Conclusion: There is increased risk of damage to the outer hair cells in Type 2 diabetes. The risk of damage to the outer
hair cells is more in the left ear than the right ear.

Key words: Outer Hair Cells; Distortion Product Otoacoustic Emissions; Type 2 Diabetes; Glycosylated Hemoglobin

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Pubmed Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari. Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 412-415. doi:10.5455/njppp.2016.6.0411404052016

Web Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari. Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions. https://www.njppp.com/?mno=226146 [Access: March 14, 2024]. doi:10.5455/njppp.2016.6.0411404052016

AMA (American Medical Association) Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari. Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 412-415. doi:10.5455/njppp.2016.6.0411404052016

Vancouver/ICMJE Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari. Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions. Natl J Physiol Pharm Pharmacol. (2016), [cited March 14, 2024]; 6(5): 412-415. doi:10.5455/njppp.2016.6.0411404052016

Harvard Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari (2016) Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions. Natl J Physiol Pharm Pharmacol, 6 (5), 412-415. doi:10.5455/njppp.2016.6.0411404052016

Turabian Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari. 2016. Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 412-415. doi:10.5455/njppp.2016.6.0411404052016

Chicago Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari. "Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 412-415. doi:10.5455/njppp.2016.6.0411404052016

MLA (The Modern Language Association) Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari. "Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions." National Journal of Physiology, Pharmacy and Pharmacology 6.5 (2016), 412-415. Print. doi:10.5455/njppp.2016.6.0411404052016

APA (American Psychological Association) Style

Rajesh Paluru, Yoganandareddy Indla, Ramaswamy Chellam, Rajani Santhakumari (2016) Assessment of functional status of outer hair cells in Type 2 diabetes by using distortion product otoacoustic emissions. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 412-415. doi:10.5455/njppp.2016.6.0411404052016

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