E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
31 / 08 / 2016

 


Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K..


Abstract
Background: Alpinia galanga belonging to Zingiberaceae family was traditionally used to treat numerous inflammatory disorders. The rationale behind its use since ages has to be scientifically validated for developing newer therapeutic agents.

Aims and Objectives: Anti-inflammatory activity of ethanolic extract of A. galanga in carrageenan induced pleurisy rats.

Materials and Methods: This study was investigated on the ethanolic extract of A. galanga rhizome by scientifically validated anti-inflammatory screening technique on rats by carrageenan induced pleurisy. This pleurisy model is considered to be an excellent acute inflammatory model in which fluid extravasations, leukocyte migration and the various biochemical parameters involved in the inflammatory response can be measured easily in the exudates.

Results: The results obtained indicate that the ethanolic extract had significant activity in rats in all the tested groups A. galanga 100, 200 and 400 mg with P < 0.005 compared to that of control.

Conclusion: The study confirms the potential anti-inflammatory activity of ethanolic extract of A. galanga rhizome.

Key words: Alpinia galanga; Inflammation; Carrageenan, Pleurisy; Rats


 
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How to Cite this Article
Pubmed Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K.. Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 468-470. doi:10.5455/njppp.2016.6.0719013072016


Web Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K.. Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats. https://www.njppp.com/?mno=235231 [Access: March 16, 2024]. doi:10.5455/njppp.2016.6.0719013072016


AMA (American Medical Association) Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K.. Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 468-470. doi:10.5455/njppp.2016.6.0719013072016



Vancouver/ICMJE Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K.. Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats. Natl J Physiol Pharm Pharmacol. (2016), [cited March 16, 2024]; 6(5): 468-470. doi:10.5455/njppp.2016.6.0719013072016



Harvard Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K. (2016) Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats. Natl J Physiol Pharm Pharmacol, 6 (5), 468-470. doi:10.5455/njppp.2016.6.0719013072016



Turabian Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K.. 2016. Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 468-470. doi:10.5455/njppp.2016.6.0719013072016



Chicago Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K.. "Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 468-470. doi:10.5455/njppp.2016.6.0719013072016



MLA (The Modern Language Association) Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K.. "Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats." National Journal of Physiology, Pharmacy and Pharmacology 6.5 (2016), 468-470. Print. doi:10.5455/njppp.2016.6.0719013072016



APA (American Psychological Association) Style

Subash K.R, Bhanu Prakash G., Vijaya Chandra Reddy K., Manjunath K., Umamaheswara Rao K. (2016) Anti-inflammatory activity of ethanolic extract of Alpinia galanga in carrageenan induced pleurisy rats. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 468-470. doi:10.5455/njppp.2016.6.0719013072016