Clonazepam-induced acute liver injury: A case report

Malini Muraleedharan Nair; Dhanya Susan Abraham; Neethu C M

doi:10.5455/njppp.2017.7.0723308072017

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Case Report

Online Publishing Date:
11 / 10 / 2017

Natl J Physiol Pharm Pharmacol. 2017; 7(12): 1439-1440

doi: 10.5455/njppp.2017.7.0723308072017

Clonazepam-induced acute liver injury: A case report

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M.

Abstract
Clonazepam belongs to the benzodiazepine class of drugs (benzodiazepine derivative). It is used both as an anticonvulsant and in the treatment of panic disorder with or without agoraphobia. The most frequent adverse drug reactions of clonazepam are sedation or drowsiness, ataxia or hypotonia, and behavioral disturbances. Hepatomegaly and transient elevations in serum aminotransferases and alkaline phosphatase concentrations may occur in patients receiving this drug, but the frequency of the reaction has not been well defined. Here, we report that an acute psychosis case was the patients laboratory reports showed a transient elevation in serum transaminases and alkaline phosphatase levels after clonazepam was administered.

Key words: Clonazepam; Benzodiazepines; Serum Transaminases; Alkaline Phosphatase; Adverse Drug Reaction

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Pubmed Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. 2017; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Web Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M. Clonazepam-induced acute liver injury: A case report. https://www.njppp.com/?mno=271177 [Access: March 14, 2024]. doi:10.5455/njppp.2017.7.0723308072017

AMA (American Medical Association) Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. 2017; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Vancouver/ICMJE Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. (2017), [cited March 14, 2024]; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Harvard Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M (2017) Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Turabian Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M. 2017. Clonazepam-induced acute liver injury: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Chicago Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M. "Clonazepam-induced acute liver injury: A case report." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

MLA (The Modern Language Association) Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M. "Clonazepam-induced acute liver injury: A case report." National Journal of Physiology, Pharmacy and Pharmacology 7.12 (2017), 1439-1440. Print. doi:10.5455/njppp.2017.7.0723308072017

APA (American Psychological Association) Style

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M (2017) Clonazepam-induced acute liver injury: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

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