E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
15 / 03 / 2022

 


A spectrum of pulmonary function test in interstitial lung diseases

Madhavi Dhameliya, Keyurkumar M Patel, Ghanshyam B Borisagar.


Abstract
Background: Diffuse parenchymal lung disease affects interstitium. Pulmonary Function Test is utilized for diagnosis, severity assessment, and treatment response. Spirometry and diffusing capacity of carbon monoxide (DLco) are commonly used in routine.

Aim and Objectives: The aim of the study was to study demography and radiology of interstitial lung diseases (ILDs) and to assess severity and progression of ILDs.

Materials and Methods: A prospective and observational study was carried out of age group >12 years at tertiary care center from October 2019 to September 2021. Participants having clinical suspicious of ILD were advised for high-decision computed tomography. Among those having ILDs were evaluated for spirometry at first visit and at 6 month. The treatment was given according to the standard guidelines protocol in between.

Results: Total 100 participants (58 male and 42 female) involved in the study. Mean (standard deviation [SD]) of age and body mass index was 49.1 (13.6) and 23.84 (4.51), respectively. Smokers, ex-smoker, and non-smoker were 32%, 10%, and 58%, respectively. Exertional dyspnea (93%) and dry cough (45%) were the most common symptoms to be encountered. Spirometry parameters such as forced expiratory volume at 1 s (FEV1), forced vital capacity (FVC), FEV1/FVC, DLco, and gender, age, and physiology index depicted 50.25 (13.56), 54.06 (13.53), 95.50 (18.35), 42.52 (11.23), and 3.30 (1.45), respectively. Significant decline in lung function was observed at 6 months (P < 0.001). Septal thickening (71%) and traction bronchiectasis (43%) were commonly observed radiological patterns.

Conclusion: The spirometry data of ILD patients have predominant restrictive pattern (moderate severity) with high incidence of IPF (Idiopathic pulmonary fibrosis). The majority ILDs are progressive in nature; lung function declined in course of time and equally distributed irrespective the smoking status.

Key words: Interstitial Lung Disease; Spirometry; Radiology; Gender, Age, and Physiology Index


 
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How to Cite this Article
Pubmed Style

Dhameliya M, Patel KM, Borisagar GB. A spectrum of pulmonary function test in interstitial lung diseases. Natl J Physiol Pharm Pharmacol. 2022; 12(4): 531-536. doi:10.5455/njppp.2022.12.02096202207032022


Web Style

Dhameliya M, Patel KM, Borisagar GB. A spectrum of pulmonary function test in interstitial lung diseases. https://www.njppp.com/?mno=92026 [Access: March 14, 2024]. doi:10.5455/njppp.2022.12.02096202207032022


AMA (American Medical Association) Style

Dhameliya M, Patel KM, Borisagar GB. A spectrum of pulmonary function test in interstitial lung diseases. Natl J Physiol Pharm Pharmacol. 2022; 12(4): 531-536. doi:10.5455/njppp.2022.12.02096202207032022



Vancouver/ICMJE Style

Dhameliya M, Patel KM, Borisagar GB. A spectrum of pulmonary function test in interstitial lung diseases. Natl J Physiol Pharm Pharmacol. (2022), [cited March 14, 2024]; 12(4): 531-536. doi:10.5455/njppp.2022.12.02096202207032022



Harvard Style

Dhameliya, M., Patel, . K. M. & Borisagar, . G. B. (2022) A spectrum of pulmonary function test in interstitial lung diseases. Natl J Physiol Pharm Pharmacol, 12 (4), 531-536. doi:10.5455/njppp.2022.12.02096202207032022



Turabian Style

Dhameliya, Madhavi, Keyurkumar M Patel, and Ghanshyam B Borisagar. 2022. A spectrum of pulmonary function test in interstitial lung diseases. National Journal of Physiology, Pharmacy and Pharmacology, 12 (4), 531-536. doi:10.5455/njppp.2022.12.02096202207032022



Chicago Style

Dhameliya, Madhavi, Keyurkumar M Patel, and Ghanshyam B Borisagar. "A spectrum of pulmonary function test in interstitial lung diseases." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 531-536. doi:10.5455/njppp.2022.12.02096202207032022



MLA (The Modern Language Association) Style

Dhameliya, Madhavi, Keyurkumar M Patel, and Ghanshyam B Borisagar. "A spectrum of pulmonary function test in interstitial lung diseases." National Journal of Physiology, Pharmacy and Pharmacology 12.4 (2022), 531-536. Print. doi:10.5455/njppp.2022.12.02096202207032022



APA (American Psychological Association) Style

Dhameliya, M., Patel, . K. M. & Borisagar, . G. B. (2022) A spectrum of pulmonary function test in interstitial lung diseases. National Journal of Physiology, Pharmacy and Pharmacology, 12 (4), 531-536. doi:10.5455/njppp.2022.12.02096202207032022