Association of metabolic status with serum orexin levels in young females

Shikha Jain; Amit Goel; Vani Gupta; Ajay Kumar Jain

doi:10.5455/njppp.2023.13.09446202315102023

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Online Publishing Date:
28 / 10 / 2023

Natl J Physiol Pharm Pharmacol. 2024; 14(5):

doi: 10.5455/njppp.2023.13.09446202315102023

Association of metabolic status with serum orexin levels in young females

Shikha Jain, Amit Goel, Vani Gupta, Ajay Kumar Jain.

Abstract
Background: Metabolic syndrome has always been linked with obesity and a sedentary lifestyle due to induction of metabolic derangements. Orexin A and B are recently discovered hypothalamic neuropeptides. Orexin A regulates appetite, food intake, and energy expenditure.

Aims and Objectives: Metabolic fuel detectors regulate energy balance at peripheral and central levels. The aim of this study is to assess association of serum orexin levels with metabolic risk markers in women of reproductive age group (RAG).

Materials and Methods: The study was conducted in the campus of King George Medical University (KGMU), Uttar Pradesh, Lucknow, INDIA. One hundred and fifty apparently healthy women of RAG, that is, 20–40 years of age were randomly selected. Fasting serum orexin and serum insulin levels were measured using enzyme-linked immunosorbent assay and weight, body mass index (BMI), fasting blood glucose, lipid profile, and blood pressure were estimated in women.

Results: The results show that serum orexin levels have significant positive correlation with fasting blood glucose, weight, BMI, and waist circumference along with a weak negative correlation with serum insulin level.

Conclusion: In the present study, serum orexin levels significantly correlate with weight, BMI, fasting blood glucose, and weak negative correlation with serum insulin levels. Serum orexin levels did not correlate with the lipid profile of women of RAG.

Key words: Orexin; Reproductive Age Group Women; Body Mass Index; Fasting Blood Glucose; Serum Insulin Levels; Serum Orexin Levels

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Pubmed Style

Jain S, Goel A, Gupta V, Jain AK. Association of metabolic status with serum orexin levels in young females. Natl J Physiol Pharm Pharmacol. Online First: 28 Oct, 2023. doi:10.5455/njppp.2023.13.09446202315102023

Web Style

Jain S, Goel A, Gupta V, Jain AK. Association of metabolic status with serum orexin levels in young females. https://www.njppp.com/?mno=169343 [Access: March 14, 2024]. doi:10.5455/njppp.2023.13.09446202315102023

AMA (American Medical Association) Style

Jain S, Goel A, Gupta V, Jain AK. Association of metabolic status with serum orexin levels in young females. Natl J Physiol Pharm Pharmacol. Online First: 28 Oct, 2023. doi:10.5455/njppp.2023.13.09446202315102023

Vancouver/ICMJE Style

Jain S, Goel A, Gupta V, Jain AK. Association of metabolic status with serum orexin levels in young females. Natl J Physiol Pharm Pharmacol, [cited March 14, 2024]; Online First: 28 Oct, 2023. doi:10.5455/njppp.2023.13.09446202315102023

Harvard Style

Jain, S., Goel, . A., Gupta, . V. & Jain, . A. K. (2024) Association of metabolic status with serum orexin levels in young females. Natl J Physiol Pharm Pharmacol, Online First: 28 Oct, 2023. doi:10.5455/njppp.2023.13.09446202315102023

Turabian Style

Jain, Shikha, Amit Goel, Vani Gupta, and Ajay Kumar Jain. 2024. Association of metabolic status with serum orexin levels in young females. National Journal of Physiology, Pharmacy and Pharmacology, Online First: 28 Oct, 2023. doi:10.5455/njppp.2023.13.09446202315102023

Chicago Style

Jain, Shikha, Amit Goel, Vani Gupta, and Ajay Kumar Jain. "Association of metabolic status with serum orexin levels in young females." National Journal of Physiology, Pharmacy and Pharmacology Online First: 28 Oct, 2023. doi:10.5455/njppp.2023.13.09446202315102023

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Jain, S., Goel, . A., Gupta, . V. & Jain, . A. K. (2024) Association of metabolic status with serum orexin levels in young females. National Journal of Physiology, Pharmacy and Pharmacology, Online First: 28 Oct, 2023. doi:10.5455/njppp.2023.13.09446202315102023

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