E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
18 / 05 / 2017

 


Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis

Atanu Roy, Sanjeev K. Singh.


Abstract
Background: Ankylosing spondylitis (AS) is an autoimmune disease which leads to the involvement of skeletal, cardiac, nervous tissues, and other systemic diseases.

Aims and Objectives: This study was conducted to assess the cardiac sympathovagal responses in the AS patients using Valsalva maneuver (VM) and tilt-table test (TTT).

Materials and Methods: A total of 30 AS patients having Bath AS Disease Activity Index of ≥4 were included in this study. The same numbers of age- and sex-matched controls were also selected. The blood pressure (BP) and electrocardiogram were recorded during VM and TTT. The Valsalva ratio and 30:15 ratio were calculated.

Results: During VM, there is a statistically significant decrease in the Valsalva ratio in the cases (P < 0.05). After TTT, there is a significant decrease in 30:15 ratio and significant increase in systolic BP (SBP) in the cases (P < 0.05).

Conclusion: The Valsalva ratio in the cases is decreased indicating the parasympathetic loss which is further supported by the decrease in 30:15 ratio observed after TTT. The increase in SBP in cases also supports the shifting of sympathovagal balance toward the sympathetic side.

Key words: Valsalva Maneuver; Tilt-Table Test; Ankylosing Spondylitis; Autonomic Nervous System


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Atanu Roy
Articles by Sanjeev K. Singh
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Atanu Roy, Sanjeev K. Singh. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 924-928. doi:10.5455/njppp.2017.7.0410120042017


Web Style

Atanu Roy, Sanjeev K. Singh. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. https://www.njppp.com/?mno=263111 [Access: March 15, 2024]. doi:10.5455/njppp.2017.7.0410120042017


AMA (American Medical Association) Style

Atanu Roy, Sanjeev K. Singh. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 924-928. doi:10.5455/njppp.2017.7.0410120042017



Vancouver/ICMJE Style

Atanu Roy, Sanjeev K. Singh. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. Natl J Physiol Pharm Pharmacol. (2017), [cited March 15, 2024]; 7(9): 924-928. doi:10.5455/njppp.2017.7.0410120042017



Harvard Style

Atanu Roy, Sanjeev K. Singh (2017) Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. Natl J Physiol Pharm Pharmacol, 7 (9), 924-928. doi:10.5455/njppp.2017.7.0410120042017



Turabian Style

Atanu Roy, Sanjeev K. Singh. 2017. Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 924-928. doi:10.5455/njppp.2017.7.0410120042017



Chicago Style

Atanu Roy, Sanjeev K. Singh. "Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 924-928. doi:10.5455/njppp.2017.7.0410120042017



MLA (The Modern Language Association) Style

Atanu Roy, Sanjeev K. Singh. "Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis." National Journal of Physiology, Pharmacy and Pharmacology 7.9 (2017), 924-928. Print. doi:10.5455/njppp.2017.7.0410120042017



APA (American Psychological Association) Style

Atanu Roy, Sanjeev K. Singh (2017) Assessment of cardiac sympathovagal activity in the patients suffering from ankylosing spondylitis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 924-928. doi:10.5455/njppp.2017.7.0410120042017