E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
08 / 01 / 2013

 


Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena.


Abstract
Background : The relationship between uric acid and microalbuminuria in healthy adults without other cardiovascular risk factors may help to clarify the role of uric acid in cardiovascular disease.
Objectives: To study and compare the association of serum uric acid levels with microalbuminuria in normotensive and prehypertensive subjects without a history of cardiovascular disease or renal dysfunction.
Material and Methods :350 subjects were included in study. All the routine investigations along with serum uric acid and urinary albumin were conducted . Microalbuminuria was detected by immunoprecipitation in a random urine sample. Serum uric acid level was estimated by Spectrophotometry.
Results:The overall prevalence of prehypertension was 38.06% (Males,39.10% and females, 35.56%). The total prevalence of microalbuminuria was 11.61% ( 9.9% of normotensives and 14.4% of prehypertensives ).Hyperuricemia was seen in 10.32% of the total study population.Among normotensives, 9% of males and 8.6% of females and in prehypertensive subjects, 14% of males & 9.4% of females had hyperuricemia. Among the prehypertensives, those with microalbuminuria had a significantly higher (p<0.001) serum uric acid level (7.024 + 1.023 mg/dl) as compared to those without microalbuminuria (5.089 +0.965mg/dl).
Conclusion:This study demonstrates a strong independent association between uric acid level and microalbuminuria in prehypertensive subjects without a history of cardiovascular disease, diabetes decreased renal function.

Key words: Microalbuminuria, Uric acid ,prehypertension, India.


 
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How to Cite this Article
Pubmed Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. Natl J Physiol Pharm Pharmacol. 2013; 3(1): 87-91. doi:10.5455/njppp.2013.3.87-91


Web Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. https://www.njppp.com/?mno=28885 [Access: March 14, 2024]. doi:10.5455/njppp.2013.3.87-91


AMA (American Medical Association) Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. Natl J Physiol Pharm Pharmacol. 2013; 3(1): 87-91. doi:10.5455/njppp.2013.3.87-91



Vancouver/ICMJE Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. Natl J Physiol Pharm Pharmacol. (2013), [cited March 14, 2024]; 3(1): 87-91. doi:10.5455/njppp.2013.3.87-91



Harvard Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena (2013) Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. Natl J Physiol Pharm Pharmacol, 3 (1), 87-91. doi:10.5455/njppp.2013.3.87-91



Turabian Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena. 2013. Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 3 (1), 87-91. doi:10.5455/njppp.2013.3.87-91



Chicago Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena. "Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study." National Journal of Physiology, Pharmacy and Pharmacology 3 (2013), 87-91. doi:10.5455/njppp.2013.3.87-91



MLA (The Modern Language Association) Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena. "Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study." National Journal of Physiology, Pharmacy and Pharmacology 3.1 (2013), 87-91. Print. doi:10.5455/njppp.2013.3.87-91



APA (American Psychological Association) Style

C L Meena, Harsa R, V K Meena, Anju Bharti, Rajani Nawal, L P Meena, Nilesh Kumar, RN Meena (2013) Association of serum uric acid and microalbuminuria in prehypertension : A cross sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 3 (1), 87-91. doi:10.5455/njppp.2013.3.87-91