E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Early diagnosis of neuropathy in diabetic patients using nerve conduction studies

Suchitra Parkhad, Sachin Palve.

Abstract
Background: Neuropathy is one of the common complications of diabetes, in which the patient’s quality of life is compromised. Nerve conduction studies (NCS) are not commonly employed to detect the neuropathy.

Aims & Objective: To find out the utility of Nerve conduction studies (NCS) as early indicator of neuropathy in diabetic patients.

Materials and Methods: 50 diabetes mellitus patients with normal HbA1c levels and 50 diabetes mellitus patients with elevated HbA1c levels were selected, making it a total of 100 diabetes mellitus patients. 50 non-diabetic, healthy subjects were chosen as a control group. The nerve conduction velocity was tested in all the diabetic subjects and the healthy controls.

Results: The analysis showed that the nerve conduction velocity progressively decreased from the controls (49.0 ± 3.9) to the diabetics with a good glycaemia control (47.2 ± 2.8), to the diabetics with a poor glycemic control (45.3 ± 3.1).

Conclusion: There is a progressive neuronal involvement in the diabetic process which is accelerated by poor glycemic control. Therefore, nerve conduction studies can be employed for testing and for the early indication of neuropathy in diabetic patients.

Key words: Nerve Conduction Velocity; HbA1c; Diabetes Mellitus; Diagnosis


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Suchitra Parkhad
Articles by Sachin Palve
on Google
on Google Scholar


REFERENCES
1. Zargar AH, Wani AI, Masoodi SR, Laway BA, Bashir MI. Mortality in diabetes mellitus – data from a developing region of the world. Diabetes Res Clin Pract. 1999; 43: 67-74. [DOI via Crossref]   
2. Tesfaye S, Stevens LK, Stephenson JM, Fuller JH, Plater M, Ionescu- Tirgoviste C, et al. Prevalence of diabetic peripheral neuropathy and its relation to glycemic control and potential risk factors. The Euro Diab IDDM complications study. Diabetologia. 1996; 39: 1377-1384. [DOI via Crossref]    [Pubmed]   
3. Perkins BA, Bril V. Diagnosis and management of diabetic neuropathy. Curr Diab Rep. 2002; 2: 495–500.
4. Partanen J, Niskanen L, Lehtinen J, Mervaala E, Siitonen O, Uusitupa M. Natural history of peripheral neuropathy in patients with non-insulindependent diabetes mellitus. NEJM. 1995; 333: 89 –94.
5. Consensus statement. Report and recommendations of the San Antonio conference on diabetic neuropathy. American Diabetic Association, American Academy of Neurology. Diabetes Care. 1988; 11: 592–7.
6. Mayurasakorn K, Somthip N, Caengow S, Chulkarat N, Wanichsuwan M. Glycemic control and microvascular complications among type 2 diabetes at primary care units. J Med Assoc Thai. 2009; 92: 1094-101. [Pubmed]   
7. Chandalia HB, Krishnaswamy PR. Glycated hemoglobin. Current Science. 2002; 83: 1522-1532.
8. Dahl-Jorgensen K, Brinchmann-Hansen O, Hanssen KF, Ganes T, Kierulf P, Smeland E, et al. Effect of near normoglycaemia for two years on progression of early diabetic retinopathy, nephropathy, andneuropathy: The Oslo Study. Br Med J. 1986; 293: 1195-1199 [DOI via Crossref]   
9. The DCCT Research Group. Factors in the development of diabetic neuropathy in feasibility phase of Diabetes Control and Complications Trial (DCCT). Diabetes. 1988; 37: 476-481. [DOI via Crossref]   
10. Bansal V, Kalita J, Misra UK. Diabetic neuropathy. Postgrad Med J. 2006; 82: 95-100. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   

How to Cite this Article
Pubmed Style

Suchitra Parkhad, Sachin Palve. Early diagnosis of neuropathy in diabetic patients using nerve conduction studies. Natl J Physiol Pharm Pharmacol. 2014; 4(2): 158-160. doi:10.5455/njppp.2014.4.041220132


Web Style

Suchitra Parkhad, Sachin Palve. Early diagnosis of neuropathy in diabetic patients using nerve conduction studies. http://www.njppp.com/?mno=38353 [Access: January 01, 2022]. doi:10.5455/njppp.2014.4.041220132


AMA (American Medical Association) Style

Suchitra Parkhad, Sachin Palve. Early diagnosis of neuropathy in diabetic patients using nerve conduction studies. Natl J Physiol Pharm Pharmacol. 2014; 4(2): 158-160. doi:10.5455/njppp.2014.4.041220132



Vancouver/ICMJE Style

Suchitra Parkhad, Sachin Palve. Early diagnosis of neuropathy in diabetic patients using nerve conduction studies. Natl J Physiol Pharm Pharmacol. (2014), [cited January 01, 2022]; 4(2): 158-160. doi:10.5455/njppp.2014.4.041220132



Harvard Style

Suchitra Parkhad, Sachin Palve (2014) Early diagnosis of neuropathy in diabetic patients using nerve conduction studies. Natl J Physiol Pharm Pharmacol, 4 (2), 158-160. doi:10.5455/njppp.2014.4.041220132



Turabian Style

Suchitra Parkhad, Sachin Palve. 2014. Early diagnosis of neuropathy in diabetic patients using nerve conduction studies. National Journal of Physiology, Pharmacy and Pharmacology, 4 (2), 158-160. doi:10.5455/njppp.2014.4.041220132



Chicago Style

Suchitra Parkhad, Sachin Palve. "Early diagnosis of neuropathy in diabetic patients using nerve conduction studies." National Journal of Physiology, Pharmacy and Pharmacology 4 (2014), 158-160. doi:10.5455/njppp.2014.4.041220132



MLA (The Modern Language Association) Style

Suchitra Parkhad, Sachin Palve. "Early diagnosis of neuropathy in diabetic patients using nerve conduction studies." National Journal of Physiology, Pharmacy and Pharmacology 4.2 (2014), 158-160. Print. doi:10.5455/njppp.2014.4.041220132



APA (American Psychological Association) Style

Suchitra Parkhad, Sachin Palve (2014) Early diagnosis of neuropathy in diabetic patients using nerve conduction studies. National Journal of Physiology, Pharmacy and Pharmacology, 4 (2), 158-160. doi:10.5455/njppp.2014.4.041220132