E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
03 / 06 / 2019

 


Central analgesic activity of ethanolic extract of Moringa oleifera seeds

Abdul Haseeb, Mohammed Ziauddin Sarkhil, Mohammed Fayazuddin, Farida Ahmad.


Abstract
Background: Moringa oleifera Lam. commonly known as the drumstick tree is an exceptionally nutritious vegetable tree with a variety of potential medicinal uses.

Aims and Objectives: The objective of this study was to evaluate the central analgesic activity of ethanolic extract of M. oleifera (EEMO) seeds.

Materials and Methods: The central analgesic activity was studied using Eddy’s hot plate method and tail immersion method in Albino Wistar rats of either sex weighing 150–200 g at doses of EEMO 50 mg/kg, 100 mg/kg, and 200 mg/kg. Statistical significance was calculated using one-way analysis of variance followed by post hoc Dunnett’s test.

Results: EEMO at all three doses 50 mg/kg, 100 mg/kg, and 200 mg/kg exhibited central analgesic activity by significantly increasing the reaction time in Eddy’s hot plate method and tail immersion method when compared to control group.

Conclusion: EEMO seeds exhibit central analgesic activity in experimental animals.

Key words: Moringa oleifera; Eddy’s Hot Plate Method; Tail Immersion Method; Central Analgesic Activity


 
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How to Cite this Article
Pubmed Style

Haseeb A, Sarkhil MZ, Fayazuddin M, Ahmad F. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. Natl J Physiol Pharm Pharmacol. 2019; 9(8): 767-770. doi:10.5455/njppp.2019.9.0519223052019


Web Style

Haseeb A, Sarkhil MZ, Fayazuddin M, Ahmad F. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. https://www.njppp.com/?mno=50053 [Access: March 15, 2024]. doi:10.5455/njppp.2019.9.0519223052019


AMA (American Medical Association) Style

Haseeb A, Sarkhil MZ, Fayazuddin M, Ahmad F. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. Natl J Physiol Pharm Pharmacol. 2019; 9(8): 767-770. doi:10.5455/njppp.2019.9.0519223052019



Vancouver/ICMJE Style

Haseeb A, Sarkhil MZ, Fayazuddin M, Ahmad F. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. Natl J Physiol Pharm Pharmacol. (2019), [cited March 15, 2024]; 9(8): 767-770. doi:10.5455/njppp.2019.9.0519223052019



Harvard Style

Haseeb, A., Sarkhil, . M. Z., Fayazuddin, . M. & Ahmad, . F. (2019) Central analgesic activity of ethanolic extract of Moringa oleifera seeds. Natl J Physiol Pharm Pharmacol, 9 (8), 767-770. doi:10.5455/njppp.2019.9.0519223052019



Turabian Style

Haseeb, Abdul, Mohammed Ziauddin Sarkhil, Mohammed Fayazuddin, and Farida Ahmad. 2019. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. National Journal of Physiology, Pharmacy and Pharmacology, 9 (8), 767-770. doi:10.5455/njppp.2019.9.0519223052019



Chicago Style

Haseeb, Abdul, Mohammed Ziauddin Sarkhil, Mohammed Fayazuddin, and Farida Ahmad. "Central analgesic activity of ethanolic extract of Moringa oleifera seeds." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 767-770. doi:10.5455/njppp.2019.9.0519223052019



MLA (The Modern Language Association) Style

Haseeb, Abdul, Mohammed Ziauddin Sarkhil, Mohammed Fayazuddin, and Farida Ahmad. "Central analgesic activity of ethanolic extract of Moringa oleifera seeds." National Journal of Physiology, Pharmacy and Pharmacology 9.8 (2019), 767-770. Print. doi:10.5455/njppp.2019.9.0519223052019



APA (American Psychological Association) Style

Haseeb, A., Sarkhil, . M. Z., Fayazuddin, . M. & Ahmad, . F. (2019) Central analgesic activity of ethanolic extract of Moringa oleifera seeds. National Journal of Physiology, Pharmacy and Pharmacology, 9 (8), 767-770. doi:10.5455/njppp.2019.9.0519223052019