Febuxostat- a new treatment for hyperuricaemia in gout - a review article

Anjana Pandey; Mridul Chaturvedi; Himanshu Prakash; Daulat; Meena

2022, Vol: 12, Issue: 8

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Review Article

Natl J Physiol Pharm Pharmacol. 2012; 2(1): 23-28

Febuxostat- a new treatment for hyperuricaemia in gout - a review article

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena.

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Abstract
Febuxostat, a novel, orally administered, potent, non–purine analogue, xanthine oxidase inhibitor in the management of hyperuricemia in patients with gout & chronic tophaceous gout. It has minimal effects on other enzymes involved in purine and pyrimidine metabolism, and is metabolized mainly by glucuronide formation and oxidation in the liver. In a study of subjects with renal impairment, the serum urate–lowering effect of febuxostat was unaltered. Febuxostat, at a daily dose of 80 mg or 120 mg, was more effective than allopurinol at the commonly used fixed daily dose of 300 mg in lowering serum urate.

Key words: Febuxostat, xanthine oxidase inhibitor, chronic tophaceous gout, renal impairment

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Pubmed Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. Natl J Physiol Pharm Pharmacol. 2012; 2(1): 23-28.

Web Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. https://www.njppp.com/?mno=9970 [Access: August 03, 2022].

AMA (American Medical Association) Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. Natl J Physiol Pharm Pharmacol. 2012; 2(1): 23-28.

Vancouver/ICMJE Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. Natl J Physiol Pharm Pharmacol. (2012), [cited August 03, 2022]; 2(1): 23-28.

Harvard Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena (2012) Febuxostat- a new treatment for hyperuricaemia in gout - a review article. Natl J Physiol Pharm Pharmacol, 2 (1), 23-28.

Turabian Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. 2012. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. National Journal of Physiology, Pharmacy and Pharmacology, 2 (1), 23-28.

Chicago Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. "Febuxostat- a new treatment for hyperuricaemia in gout - a review article." National Journal of Physiology, Pharmacy and Pharmacology 2 (2012), 23-28.

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena (2012) Febuxostat- a new treatment for hyperuricaemia in gout - a review article. National Journal of Physiology, Pharmacy and Pharmacology, 2 (1), 23-28.



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