E-ISSN 2231-3206 | ISSN 2320-4672
 

Review Article 


Febuxostat- a new treatment for hyperuricaemia in gout - a review article

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena.

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Abstract
Febuxostat, a novel, orally administered, potent, non–purine analogue, xanthine oxidase inhibitor in the management of hyperuricemia in patients with gout & chronic tophaceous gout. It has minimal effects on other enzymes involved in purine and pyrimidine metabolism, and is metabolized mainly by glucuronide formation and oxidation in the liver. In a study of subjects with renal impairment, the serum urate–lowering effect of febuxostat was unaltered. Febuxostat, at a daily dose of 80 mg or 120 mg, was more effective than allopurinol at the commonly used fixed daily dose of 300 mg in lowering serum urate.

Key words: Febuxostat, xanthine oxidase inhibitor, chronic tophaceous gout, renal impairment


 
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How to Cite this Article
Pubmed Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. Natl J Physiol Pharm Pharmacol. 2012; 2(1): 23-28.


Web Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. http://www.njppp.com/?mno=9970 [Access: January 02, 2022].


AMA (American Medical Association) Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. Natl J Physiol Pharm Pharmacol. 2012; 2(1): 23-28.



Vancouver/ICMJE Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. Natl J Physiol Pharm Pharmacol. (2012), [cited January 02, 2022]; 2(1): 23-28.



Harvard Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena (2012) Febuxostat- a new treatment for hyperuricaemia in gout - a review article. Natl J Physiol Pharm Pharmacol, 2 (1), 23-28.



Turabian Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. 2012. Febuxostat- a new treatment for hyperuricaemia in gout - a review article. National Journal of Physiology, Pharmacy and Pharmacology, 2 (1), 23-28.



Chicago Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. "Febuxostat- a new treatment for hyperuricaemia in gout - a review article." National Journal of Physiology, Pharmacy and Pharmacology 2 (2012), 23-28.



MLA (The Modern Language Association) Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena. "Febuxostat- a new treatment for hyperuricaemia in gout - a review article." National Journal of Physiology, Pharmacy and Pharmacology 2.1 (2012), 23-28. Print.



APA (American Psychological Association) Style

Anjana Pandey, Mridul Chaturvedi, Himanshu Prakash, Daulat, Meena (2012) Febuxostat- a new treatment for hyperuricaemia in gout - a review article. National Journal of Physiology, Pharmacy and Pharmacology, 2 (1), 23-28.