E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
03 / 03 / 2017

 


Effect of family history of hypertension on the autonomic nervous system in normotensive individuals

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar.


Abstract
Background: Hypertension is a major public health problem, which usually has a silent modus operandi. It is the outcome of a complex interaction between genetic and environmental factors.

Aims and Objective: The aim of this study is to evaluate the autonomic nervous system (ANS) in normotensive individuals albeit with a family history of hypertension.

Materials and Methods: This study was based on the examination of the ANS, using a battery of autonomic function tests done on 30 normotensive subjects with a family history of hypertension and an equal number of age and sex-matched controls without any such family history. The results were statistically analyzed using Student’s unpaired t-test for comparison of means. P < 0.05 was considered as statistically significant.

Results: Both the study groups are well matched as far the anthropometric variables, as well as the resting cardiovascular parameters are concerned. The parasympathetic component of the ANS was also essentially similar in its functionality in both the groups. Whereas, the sympathetic component was overactive in the participants as exemplified by greater increase in the diastolic blood pressure in response to sustained handgrip.

Conclusion: The normotensive individuals with a family history of hypertension in this study showed an overactive sympathetic nervous system and an unaffected parasympathetic nervous system.

Key words: Autonomic Nervous System; Family History; Hypertension


 
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How to Cite this Article
Pubmed Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar. Effect of family history of hypertension on the autonomic nervous system in normotensive individuals. Natl J Physiol Pharm Pharmacol. 2017; 7(6): 634-636. doi:10.5455/njppp.2017.7.0203023022017


Web Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar. Effect of family history of hypertension on the autonomic nervous system in normotensive individuals. https://www.njppp.com/?mno=258672 [Access: March 14, 2024]. doi:10.5455/njppp.2017.7.0203023022017


AMA (American Medical Association) Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar. Effect of family history of hypertension on the autonomic nervous system in normotensive individuals. Natl J Physiol Pharm Pharmacol. 2017; 7(6): 634-636. doi:10.5455/njppp.2017.7.0203023022017



Vancouver/ICMJE Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar. Effect of family history of hypertension on the autonomic nervous system in normotensive individuals. Natl J Physiol Pharm Pharmacol. (2017), [cited March 14, 2024]; 7(6): 634-636. doi:10.5455/njppp.2017.7.0203023022017



Harvard Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar (2017) Effect of family history of hypertension on the autonomic nervous system in normotensive individuals. Natl J Physiol Pharm Pharmacol, 7 (6), 634-636. doi:10.5455/njppp.2017.7.0203023022017



Turabian Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar. 2017. Effect of family history of hypertension on the autonomic nervous system in normotensive individuals. National Journal of Physiology, Pharmacy and Pharmacology, 7 (6), 634-636. doi:10.5455/njppp.2017.7.0203023022017



Chicago Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar. "Effect of family history of hypertension on the autonomic nervous system in normotensive individuals." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 634-636. doi:10.5455/njppp.2017.7.0203023022017



MLA (The Modern Language Association) Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar. "Effect of family history of hypertension on the autonomic nervous system in normotensive individuals." National Journal of Physiology, Pharmacy and Pharmacology 7.6 (2017), 634-636. Print. doi:10.5455/njppp.2017.7.0203023022017



APA (American Psychological Association) Style

Sneha Nandre, Shivakumar Jagadeesan, Kararshah F Kammar (2017) Effect of family history of hypertension on the autonomic nervous system in normotensive individuals. National Journal of Physiology, Pharmacy and Pharmacology, 7 (6), 634-636. doi:10.5455/njppp.2017.7.0203023022017