E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
19 / 05 / 2017

 


Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel.


Abstract
Background: Post-menopausal women suffer from various complications like autonomic dysfunction which predisposes them to cardiovascular morbidity. Decline in estrogen levels after menopause is associated with increased cardiovascular risks. Timely evaluation of such derangements and active intervention can play an important role in the prevention of cardiovascular morbidity.

Aims and Objective: The aim is to compare the sympathetic autonomic nervous system activity in pre-menopausal and age-matched post-menopausal women.

Materials and Methods: This study was conducted on two groups of 40 women each. Group I included pre-menopausal women and Group II included post-menopausal women. Sympathetic nervous system assessment was done using cold pressor test (CPT), handgrip test (HGT), and blood pressure (BP) response to standing. Statistical analysis was performed using Student’s t-test.

Results: Evaluation of sympathetic functions between the two groups showed that the mean rise in systolic BP (SBP) in response to CPT was lower in Group I than in Group II (P < 0.01). Mean rise in the diastolic BP (DBP) in response to HGT was also lower in Group I as compared to Group II (P < 0.01). Fall in SBP on standing in Group I was more than in Group II (P < 0.01).

Conclusion: Sympathetic nervous system evaluation showed sympathetic hyperactivity in the post-menopausal group as compared to the premenopausal group.

Key words: Menopause; Sympathetic; Cardiovascular; Estrogen


 
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How to Cite this Article
Pubmed Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel. Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 968-971. doi:10.5455/njppp.2017.7.0514611052017


Web Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel. Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women. https://www.njppp.com/?mno=265610 [Access: March 15, 2024]. doi:10.5455/njppp.2017.7.0514611052017


AMA (American Medical Association) Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel. Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 968-971. doi:10.5455/njppp.2017.7.0514611052017



Vancouver/ICMJE Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel. Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women. Natl J Physiol Pharm Pharmacol. (2017), [cited March 15, 2024]; 7(9): 968-971. doi:10.5455/njppp.2017.7.0514611052017



Harvard Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel (2017) Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women. Natl J Physiol Pharm Pharmacol, 7 (9), 968-971. doi:10.5455/njppp.2017.7.0514611052017



Turabian Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel. 2017. Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 968-971. doi:10.5455/njppp.2017.7.0514611052017



Chicago Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel. "Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 968-971. doi:10.5455/njppp.2017.7.0514611052017



MLA (The Modern Language Association) Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel. "Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women." National Journal of Physiology, Pharmacy and Pharmacology 7.9 (2017), 968-971. Print. doi:10.5455/njppp.2017.7.0514611052017



APA (American Psychological Association) Style

Sheveta Dureja, Vikram Bhandari, Kailash Chander Manchanda, Ram Sarup Sharma, Mridu Gupta, Rachna Bachhel (2017) Comparative analysis of sympathetic nervous system activity in pre‑menopausal and post-menopausal women. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 968-971. doi:10.5455/njppp.2017.7.0514611052017