Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital

Swetha K; Shailendar Singh; Jyothi D B

doi:10.5455/njppp.2022.12.12462202129122021

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Natl J Physiol Pharm Pharmacol. 2022; 12(8):

doi: 10.5455/njppp.2022.12.12462202129122021

Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital

Swetha K, Shailendar Singh, Jyothi D B.

Abstract
Background: Pediatric diarrhea is one of the major causes of childhood mortality around the world. Oral rehydrationtherapy (ORT) along with zinc supplementation can reduce the irrational antimicrobial use and stay in hospital.

Aims and Objectives: This study aims to evaluate the role of zinc in reduction of stool frequency and duration of diarrheal episode.

Materials and Methods: A prospective observational study was performed for 12 months at pediatric in-patient unit of BRIMS teaching hospital, Bidar. We evaluated 400 prescriptions of acute diarrhea cases for the role of zinc based on reduction of stool frequency and decrease in the duration of diarrheal episode.

Results: A study revealed a very statistically significant reduction (P < 0.001) in both stool frequencies during the 3rd5th day and there was reduction in mean duration of diarrheal episode in the group treated with ORT/parenteral rehydration+ zinc.

Conclusion: We observed significant decrease in both stool frequency and mean duration of diarrheal episodes in the group treated with ORT/parenteral rehydration+ zinc as compared to ORT/parenteral rehydration alone. Thus, we recommend practitioners to use ORS and zinc which reduces the stay in hospital and helps in faster recovery. And also, it would definitely reduce the practice of polypharmacy and inappropriate antibiotic prescribing practices.

Key words: Acute Diarrhea; Children; ORS; Zinc; World Health Organization; Indian Academic of Pediatrics

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Pubmed Style

K S, Singh S, B JD. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. Natl J Physiol Pharm Pharmacol. Online First: 03 Jan, 2022. doi:10.5455/njppp.2022.12.12462202129122021

Web Style

K S, Singh S, B JD. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. https://www.njppp.com/?mno=80242 [Access: May 02, 2022]. doi:10.5455/njppp.2022.12.12462202129122021

AMA (American Medical Association) Style

K S, Singh S, B JD. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. Natl J Physiol Pharm Pharmacol. Online First: 03 Jan, 2022. doi:10.5455/njppp.2022.12.12462202129122021

Vancouver/ICMJE Style

K S, Singh S, B JD. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. Natl J Physiol Pharm Pharmacol, [cited May 02, 2022]; Online First: 03 Jan, 2022. doi:10.5455/njppp.2022.12.12462202129122021

Harvard Style

K, S., Singh, . S. & B, . J. D. (2022) Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. Natl J Physiol Pharm Pharmacol, Online First: 03 Jan, 2022. doi:10.5455/njppp.2022.12.12462202129122021

Turabian Style

K, Swetha, Shailendar Singh, and Jyothi D B. 2022. Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. National Journal of Physiology, Pharmacy and Pharmacology, Online First: 03 Jan, 2022. doi:10.5455/njppp.2022.12.12462202129122021

Chicago Style

K, Swetha, Shailendar Singh, and Jyothi D B. "Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital." National Journal of Physiology, Pharmacy and Pharmacology Online First: 03 Jan, 2022. doi:10.5455/njppp.2022.12.12462202129122021

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

K, S., Singh, . S. & B, . J. D. (2022) Assessment of role of zinc in the management of acute diarrhea in children at a teaching hospital. National Journal of Physiology, Pharmacy and Pharmacology, Online First: 03 Jan, 2022. doi:10.5455/njppp.2022.12.12462202129122021



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