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Online Publishing Date:
25 / 02 / 2020

 


Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones

Srikrishna Sasi Ratnakaram, Elizabeth Rani Reddy.


Abstract
Background: Diagnosing polycystic ovarian syndrome (PCOS) is utmost important to treat accurately and also to assess further complications, as PCOS has higher rates of endometrial cancer, cardiovascular disease, dyslipidemia, and type 2 diabetes mellitus.

Aims and Objectives: The objectives of this study were to know the clinical features of PCOS and to know the association of PCOS with gonadotropin hormones and body mass index (BMI).

Materials and Methods: A prospective study conducted on PCOS patients from January 2018 to April 2019. PCOS was diagnosed by clinical, laboratory, and radiological investigations. PCOS patients were advised to undergo gonadotropin hormones analysis.

Results: About 50% of patients with oligomenorrhea, acne, hirsutism, and polycystic ovaries had luteinizing hormone/follicular-stimulating hormone (LH/FSH) ratio >2/1. Around 60% of patients with polycystic ovaries had BMI <25. Around 20% of patients with hirsutism, acne, and oligomenorrhea had BMI >25. Polycystic ovaries have shown signification in relation to LH/FSH >2/1 (95% confidence interval [CI] 2.05–31.09; P = 0.002), FSH ≥7 (95% CI 0.02–0.40; P = 0.001), and LH ≥10 (95% CI 0.05–0.75; P = 0.001).

Conclusion: PCOS diagnosis is a multidisciplinary approach should be evaluated by clinical features, hormonal evaluation, and radiological investigations. Diagnosing polycystic ovaries by ultrasonography and hyperandrogenism are a hallmark for PCOS.

Key words: Clinical Features; Gonadotropin Hormones; Polycystic Ovarian Syndrome


 
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Pubmed Style

Ratnakaram SS, Reddy ER. Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones. Natl J Physiol Pharm Pharmacol. 2020; 10(4): 285-289. doi:10.5455/njppp.2020.10.02035202015022020

Web Style

Ratnakaram SS, Reddy ER. Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones. https://www.njppp.com/?mno=85064 [Access: March 14, 2024]. doi:10.5455/njppp.2020.10.02035202015022020

AMA (American Medical Association) Style

Ratnakaram SS, Reddy ER. Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones. Natl J Physiol Pharm Pharmacol. 2020; 10(4): 285-289. doi:10.5455/njppp.2020.10.02035202015022020


Vancouver/ICMJE Style

Ratnakaram SS, Reddy ER. Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones. Natl J Physiol Pharm Pharmacol. (2020), [cited March 14, 2024]; 10(4): 285-289. doi:10.5455/njppp.2020.10.02035202015022020


Harvard Style

Ratnakaram, S. S. & Reddy, . E. R. (2020) Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones. Natl J Physiol Pharm Pharmacol, 10 (4), 285-289. doi:10.5455/njppp.2020.10.02035202015022020


Turabian Style

Ratnakaram, Srikrishna Sasi, and Elizabeth Rani Reddy. 2020. Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones. National Journal of Physiology, Pharmacy and Pharmacology, 10 (4), 285-289. doi:10.5455/njppp.2020.10.02035202015022020


Chicago Style

Ratnakaram, Srikrishna Sasi, and Elizabeth Rani Reddy. "Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones." National Journal of Physiology, Pharmacy and Pharmacology 10 (2020), 285-289. doi:10.5455/njppp.2020.10.02035202015022020


MLA (The Modern Language Association) Style

Ratnakaram, Srikrishna Sasi, and Elizabeth Rani Reddy. "Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones." National Journal of Physiology, Pharmacy and Pharmacology 10.4 (2020), 285-289. Print. doi:10.5455/njppp.2020.10.02035202015022020


APA (American Psychological Association) Style

Ratnakaram, S. S. & Reddy, . E. R. (2020) Association of clinical features of polycystic ovarian syndrome with body mass index and gonadotropin hormones. National Journal of Physiology, Pharmacy and Pharmacology, 10 (4), 285-289. doi:10.5455/njppp.2020.10.02035202015022020


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