E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan

Manoj Kumar Saurabh, Rakesh Kumar Karnani.

Cited by (1)

Abstract
Background: Underreporting of adverse drug reactions (ADRs) by clinician is a common problem. As interns will be budding doctors to serve the community, this study was undertaken to evaluate knowledge, attitude and perception about ADR and pharmacovigilance in them.

Aims and Objective: To assess knowledge, attitude and perceptions of interns about ADR and pharmacovigilance program and find out possible ways of improving spontaneous reporting.

Materials and Methods: A cross-section questionnaire-based study was conducted after approval by ethics committee. Pretested and validated questions consisting of 20 questions (knowledge 12, attitude 4, and perception 4) were administered to 68 interns. The filled questionnaires were collected and analyzed on Microsoft Excel sheet.

Result: All interns were well aware of term “pharmacovigilance.” They have an idea to where they should report ADR and about the nearest AMC center but only 3.33% were able to differentiate adverse effect and adverse event. Only 27.94% of the interns were revealing clear knowledge about who could report and types of the ADR to be reported at adverse drug monitoring center. Nobody was able to explain “rechallenge” or “dechallenge” in reference to ADRs 100% correctly. Majority of interns (85.29%) had not reported even single case of ADR till date. Poor reporting among interns were because of various reasons, which were busy in preparing postgraduate entrance examination (51.47%), problems in communicating patients (22.06%), inadequate training (22.06%), unavailability ADR form (4.41%), and overload of work (1.47%). Majority of interns (73.52%) were comfortable in ADR reporting by means of telephone. Of 68 interns, 48 (70.59%) supported that ADR reporting exercises should be taught in pharmacology practical classes.

Conclusion: The deficit in ADR reporting can be resolved if we adequately train our undergraduates regarding ADR reporting system, how to report, importance of reporting, and their obligation to report.

Key words: Adverse Drug Reactions (ADRs), Interns, Pharmacovigilance, Spontaneous Reporting


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Manoj Kumar Saurabh
Articles by Rakesh Kumar Karnani
on Google
on Google Scholar


REFERENCES
1. Pharmacovigilance Programme of India (PvPI) for Assuring Drug Safety. Available at: http://www.cdsco.nic.in/pharmacovigilance. htm Pharmacovigilance Programme of India (PvPI) for Assuring Drug Safety. Available athttp://www.cdsco.nic.in/pharmacovigilance.htm.
2. World Health Organization. International drug monitoring: the role of national centres. Report of a WHO meeting. World Health Organ Tech Rep Ser. 1972;498:1-25.
3. Srinivasan R, Ramya G. Adverse drug reaction causality assessment. Int J Res Pharm Chem. 2011;1(3):606-11.
4. Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18820 patients. Br Med J. 2004;329:15-9. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
5. Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA. 1998;279:1200-55. [DOI via Crossref]    [Pubmed]   
6. World Health Organization. Safety of Medicines: A Guide to Detecting and Reporting Adverse Drug Reactions. Geneva, Switzerland: WHO/EDM/QSM, 2002.
7. Sangeetha. Pharmacovigilance: the extent of awareness among the final year students, interns and postgraduates in a government teaching hospital. J Clin Diagn Res. 2012;6(7):1248-53.
8. Elizabeth ST, Kia RA, Yagnik RM, Nagaraju K. Knowledge, attitude and skills of nurses of Delhi towards adverse drug reaction reporting. Indian J Pharm Pract. 2012;5:45-51.
9. Pharmacovigilance Programme in India (PvPI)—Indian Scenario. Available at: http://www.ipc.gov.in/PvPI/Pv_home.html [accessed November 6, 2015] Pharmacovigilance Programme in India (PvPI)—Indian Scenario. Available at: http://www.ipc.gov.in/PvPI/Pv_home.html [accessed November 6, 2015].
10. Gupta P, Udupa A. Adverse drug reaction reporting and pharmacovigilance: knowledge, attitudes and perceptions amongst resident doctors. J Pharm Sci Res. 2011;3:1064-9.
11. Desi CK, Iyer G, Panchal J, Sah S, Dixit RK. An evolution of knowledge, attitude and practice of adverse drug reaction reporting among prescribers at a tertiary care hospital. Perspect Clin Res. 2011;2:129-36. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
12. Singh H, Bajaj JK, Kumar R. A survey on the knowledge, attitude, and the practice of pharmacovigilance among the health care professional in a teaching hospital in northern India. J Clin Diagn Res. 2013;7:97-9.
13. Subish P, Izham MM, Mishra P. Evolution of knowledge, attitude and practices on adverse drug reactions and pharmacovigilance in a Nepalese hospital: a preliminary study. Internet J Pharmacol. 2008;6:1.
14. Ramesh M, Parthasarathi G. Adverse drug reaction reporting, attitudes and perceptions of medical practitioners. Asian J Pharm Clin Res. 2009;2:10-4.
15. Oshikoya KA, Awobusuyi JO. Perceptions of doctors to adverse drug reaction reporting in a teaching hospital in Lagos, Nigeria. BMC Clin Pharmacol. 2009;9:14. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
16. Belton KJ, Lewis SC, Payne S, Rawlins MD, Wood S. Attitudinal survey of adverse drug reaction reporting by medical practitioners in the United Kingdom. Br J Clin Pharmacol. 1995;39:223-6. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
17. Tabeli M, Jeschke E, Bockelbrink A, Willich SN, Ostermann T, Matthes H. An educational intervention to improve the physician reporting of adverse drug reaction (ADRs) in a primary care setting in complementary and alternative medicines programs. BMC Public Health. 2009;9:274. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
18. Saurabh MK, Agrawal J. The opinion of undergraduate medical students on current curriculum and teaching methodology of pharmacology in four medical colleges of India: a questionnaire based study Int J Basic Clin Pharmacol. 2015;4(5):970-5.
19. Naeem SS, Rizvi W, Kumar A. Revisiting undergraduate practical pharmacology. J Pharmacol Pharmacother. 2012;3(1):76-9. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
20. Upadhyaya HB, Vora MB, Nagar JG, Patel PB. Knowledge, attitude and practices toward pharmacovigilance and adverse drug reactions in postgraduate students of tertiary care hospital in Gujarat. J Adv Pharm Technol Res. 2015;6:29-34. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
21. de Langen J, van Hunsel F, Passier A, de Jong-van den Beg LT, van Grootheest K. Adverse drug reporting by patients in the Netherlands: three years of experience. Drug Saf. 2008;31:514-24 [DOI via Crossref]   

This Article Cited By the following articles

Urgent need to modernize pharmacovigilance education in healthcare curricula: review of the literature
Eur J Clin Pharmacol 2018; (): .

1
 
How to Cite this Article
Pubmed Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani. An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan. Natl J Physiol Pharm Pharmacol. 2016; 6(2): 111-115. doi:10.5455/njppp.2016.6.3110201593


Web Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani. An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan. https://www.njppp.com/?mno=206710 [Access: June 02, 2022]. doi:10.5455/njppp.2016.6.3110201593


AMA (American Medical Association) Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani. An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan. Natl J Physiol Pharm Pharmacol. 2016; 6(2): 111-115. doi:10.5455/njppp.2016.6.3110201593



Vancouver/ICMJE Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani. An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan. Natl J Physiol Pharm Pharmacol. (2016), [cited June 02, 2022]; 6(2): 111-115. doi:10.5455/njppp.2016.6.3110201593



Harvard Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani (2016) An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan. Natl J Physiol Pharm Pharmacol, 6 (2), 111-115. doi:10.5455/njppp.2016.6.3110201593



Turabian Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani. 2016. An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan. National Journal of Physiology, Pharmacy and Pharmacology, 6 (2), 111-115. doi:10.5455/njppp.2016.6.3110201593



Chicago Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani. "An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 111-115. doi:10.5455/njppp.2016.6.3110201593



MLA (The Modern Language Association) Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani. "An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan." National Journal of Physiology, Pharmacy and Pharmacology 6.2 (2016), 111-115. Print. doi:10.5455/njppp.2016.6.3110201593



APA (American Psychological Association) Style

Manoj Kumar Saurabh, Rakesh Kumar Karnani (2016) An evaluation of knowledge, attitude and perception about adverse drug reactions and pharmacovigilance among intern doctors at a teaching hospital of Rajasthan. National Journal of Physiology, Pharmacy and Pharmacology, 6 (2), 111-115. doi:10.5455/njppp.2016.6.3110201593