Abstract
Background: One of the most frequent problems affecting perimenopausal women is thyroid dysfunction, symptoms of which might be so subtle that they go unrecognized for a long time. In older women, subclinical hypothyroidism (SCH) is frequent. A significant percentage of individuals are at risk of developing primary hypothyroidism as a result of their SCH.

Aim and Objectives: The goal of this study is to know the incidence of thyroid dysfunction and its clinical manifestations, to determine thyroid profile the incidence of SCH, and its relation with the cholesterol levels in perimenopausal women in patients who visit gynecology outpatient department.

Materials and Methods: The present study is a descriptive cross-sectional research undertaken in the department of the research comprised 100 women between the ages of 40 and 55 Patients were assessed using a complete history, clinical examination, and laboratory tests such as ELISA was used to test thyroid function in the serum of all patients diagnosed with SCH and also assessed serum cholesterol in patients with SCH.

Results: There were 100 patients in the present study and all were women were between the ages of 40 and 55. Menorrhagia was the most common menstrual disorder seen in the study group, with 56% of patients experiencing it. 32% of patients developed oligomenorrhea, which is one of the most common perimenopausal symptoms. Menstrual irregularities (88%) and weight increase were common symptoms in thyroid insufficiency individuals. (65%), irritation and mood changes (74%) Anxiety and sadness (61%) are the most common symptoms, followed by loss of employment. Sexual libido (5%) Subjects with normal free t3 and t4 but increased serum thyroid-stimulating hormone were classified as SCH. 20 of the patients had SCH, 4 had overt hypothyroidism, and the other 76 were euthyroid. Seventy-five percent of the patients with SCH had hypercholesterolemia when they were diagnosed.

Conclusion: We propose that perimenopausal women with or without symptoms be routinely screened based on the findings of this study. Early diagnosis and treatment of these issues will aid in lowering morbidity and preventing subsequent consequences.

Key words: Thyroid Dysfunction; Perimenopausal Women; Subclinical Hypothyroidism