Serum potassium levels of patients on angiotensin converting enzyme inhibitors  A cross-sectional study

Vishnupriya Ramakrishnan; Suganeshwari Soundarapandian

doi:10.5455/njppp.2020.10.07204202010082020

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Original Research
Online Published: 22 Aug 2020

Natl J Physiol Pharm Pharmacol. 2020; 10(12): 1076-1079

doi: 10.5455/njppp.2020.10.07204202010082020

Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study

Vishnupriya Ramakrishnan, Suganeshwari Soundarapandian.

Abstract
Background: Angiotensin-converting enzyme (ACE) inhibitors are commonly used in clinical practice to treat hypertension. Hyperkalemia develops in approximately 10% of outpatients within a year of prescription of these drugs.

Aim and Objective: The aim of this study was to identify the prevalence of hyperkalemia among outpatients who are taking ACE inhibitors for hypertension for more than 6 months.

Materials and Methods: This was a cross-sectional study conducted in the Hypertension Clinic, Tirunelveli Medical College. Around 152 hypertensive patients taking ACE inhibitors for more than 6 months were enrolled in the study. Blood samples were obtained, and their serum potassium levels were measured.

Results: Among 152 patients, there were 88 male patients (57.9%) and 64 female patients (42.1%). Ten patients (35.71%) out of 18 patients who were on monotherapy presented with hyperkalemia and 20 patients (16.12%) out of 104 patients who were on combination therapy had hyperkalemia. A higher number of patients with hyperkalemia falls in the age group of 4660 years of age. Out of 152 patients who took enalapril, 30 patients (19.73%) were found to have hyperkalemia. Of them, 20 patients (13.15%) had mild hyperkalemia, and ten patients (6.57%) had moderate hyperkalemia. There were no cases of severe hyperkalemia.

Conclusion: Hence, it is of considerable importance for physicians to identify patients at risk by regular monitoring and to implement measures to lessen the likelihood of the development of hyperkalemia.

Key words: Hyperkalemia; Hypertension; Angiotensin-converting enzyme inhibitors

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Pubmed Style

Ramakrishnan V, Soundarapandian S. Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2020; 10(12): 1076-1079. doi:10.5455/njppp.2020.10.07204202010082020

Web Style

Ramakrishnan V, Soundarapandian S. Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study. https://www.njppp.com/?mno=113123 [Access: June 27, 2026]. doi:10.5455/njppp.2020.10.07204202010082020

AMA (American Medical Association) Style

Ramakrishnan V, Soundarapandian S. Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2020; 10(12): 1076-1079. doi:10.5455/njppp.2020.10.07204202010082020

Vancouver/ICMJE Style

Ramakrishnan V, Soundarapandian S. Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study. Natl J Physiol Pharm Pharmacol. (2020), [cited June 27, 2026]; 10(12): 1076-1079. doi:10.5455/njppp.2020.10.07204202010082020

Harvard Style

Ramakrishnan, V. & Soundarapandian, . S. (2020) Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study. Natl J Physiol Pharm Pharmacol, 10 (12), 1076-1079. doi:10.5455/njppp.2020.10.07204202010082020

Turabian Style

Ramakrishnan, Vishnupriya, and Suganeshwari Soundarapandian. 2020. Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 10 (12), 1076-1079. doi:10.5455/njppp.2020.10.07204202010082020

Chicago Style

Ramakrishnan, Vishnupriya, and Suganeshwari Soundarapandian. "Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 10 (2020), 1076-1079. doi:10.5455/njppp.2020.10.07204202010082020

MLA (The Modern Language Association) Style

Ramakrishnan, Vishnupriya, and Suganeshwari Soundarapandian. "Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 10.12 (2020), 1076-1079. Print. doi:10.5455/njppp.2020.10.07204202010082020

APA (American Psychological Association) Style

Ramakrishnan, V. & Soundarapandian, . S. (2020) Serum potassium levels of patients on angiotensin converting enzyme inhibitors A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 10 (12), 1076-1079. doi:10.5455/njppp.2020.10.07204202010082020

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