Age related changes in serum dihydrotestosterone levels among type 2 diabetic males

Sanket Jheetay; Rinku Garg; Devesh Kumar; Ritu Adhana; Jayballabh Kumar; Himani Muniyal; Jaspreet Kaur

doi:10.5455/njppp.2023.13.11537202207122022

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Online Publishing Date:
19 / 12 / 2022

Natl J Physiol Pharm Pharmacol. 2023; 13(7): 1391-1396

doi: 10.5455/njppp.2023.13.11537202207122022

Age related changes in serum dihydrotestosterone levels among type 2 diabetic males

Sanket Jheetay, Rinku Garg, Devesh Kumar, Ritu Adhana, Jayballabh Kumar, Himani Muniyal, Jaspreet Kaur.

Abstract
Background: Interest in the physiological range of androgens in middle-aged men has recently increased since many illnesses, deaths, or male-specific disturbances are linked to androgen deficiency. It is yet unknown how dihydrotestosterone (DHT) levels have changed over time in the Indian population.

Aims and Objectives: The purpose of the study was to measure the levels of DHT in males as age. The absence of data on DHT levels in ageing males in the Indian population would allow for comparisons with future studies from other subcontinents.

Materials and Methods: In this study, residents of Moradabad, Uttar Pradesh, are the subjects of an observational and comparative case–control study.

Results: A total of 210 samples were collected, including 105 diabetic men and 105 controls, samples were divided into each of the three age brackets 30–40 years, 40–50 years, and 50–60 years. Compared to controls, who had a total mean DHT of 446.76 ± 265.31 pg/ml, diabetics’ total mean DHT was lower at 230.66 ± 182.02 pg/ml. The same was seen when diabetic samples and controls were compared by age groups. When age groups of diabetic samples and controls were compared there was no decline with the age group, there was a non-significant association in their comparison. When all of the samples were included, there was a non-significant reduction in DHT levels as the age groups progressed, although a decline was observed.

Conclusions: Age-related declines in serum DHT hormone levels occur over time but are not very significant.

Key words: Dihydrotestosterone; Androgen; Type 2 Diabetes mellitus

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How to Cite this Article

Pubmed Style

Jheetay S, Garg R, Kumar D, Adhana R, Kumar J, Muniyal H, Kaur J. Age related changes in serum dihydrotestosterone levels among type 2 diabetic males. Natl J Physiol Pharm Pharmacol. 2023; 13(7): 1391-1396. doi:10.5455/njppp.2023.13.11537202207122022

Web Style

Jheetay S, Garg R, Kumar D, Adhana R, Kumar J, Muniyal H, Kaur J. Age related changes in serum dihydrotestosterone levels among type 2 diabetic males. https://www.njppp.com/?mno=128498 [Access: March 14, 2024]. doi:10.5455/njppp.2023.13.11537202207122022

AMA (American Medical Association) Style

Jheetay S, Garg R, Kumar D, Adhana R, Kumar J, Muniyal H, Kaur J. Age related changes in serum dihydrotestosterone levels among type 2 diabetic males. Natl J Physiol Pharm Pharmacol. 2023; 13(7): 1391-1396. doi:10.5455/njppp.2023.13.11537202207122022

Vancouver/ICMJE Style

Jheetay S, Garg R, Kumar D, Adhana R, Kumar J, Muniyal H, Kaur J. Age related changes in serum dihydrotestosterone levels among type 2 diabetic males. Natl J Physiol Pharm Pharmacol. (2023), [cited March 14, 2024]; 13(7): 1391-1396. doi:10.5455/njppp.2023.13.11537202207122022

Harvard Style

Jheetay, S., Garg, . R., Kumar, . D., Adhana, . R., Kumar, . J., Muniyal, . H. & Kaur, . J. (2023) Age related changes in serum dihydrotestosterone levels among type 2 diabetic males. Natl J Physiol Pharm Pharmacol, 13 (7), 1391-1396. doi:10.5455/njppp.2023.13.11537202207122022

Turabian Style

Jheetay, Sanket, Rinku Garg, Devesh Kumar, Ritu Adhana, Jayballabh Kumar, Himani Muniyal, and Jaspreet Kaur. 2023. Age related changes in serum dihydrotestosterone levels among type 2 diabetic males. National Journal of Physiology, Pharmacy and Pharmacology, 13 (7), 1391-1396. doi:10.5455/njppp.2023.13.11537202207122022

Chicago Style

Jheetay, Sanket, Rinku Garg, Devesh Kumar, Ritu Adhana, Jayballabh Kumar, Himani Muniyal, and Jaspreet Kaur. "Age related changes in serum dihydrotestosterone levels among type 2 diabetic males." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 1391-1396. doi:10.5455/njppp.2023.13.11537202207122022

MLA (The Modern Language Association) Style

Jheetay, Sanket, Rinku Garg, Devesh Kumar, Ritu Adhana, Jayballabh Kumar, Himani Muniyal, and Jaspreet Kaur. "Age related changes in serum dihydrotestosterone levels among type 2 diabetic males." National Journal of Physiology, Pharmacy and Pharmacology 13.7 (2023), 1391-1396. Print. doi:10.5455/njppp.2023.13.11537202207122022

APA (American Psychological Association) Style

Jheetay, S., Garg, . R., Kumar, . D., Adhana, . R., Kumar, . J., Muniyal, . H. & Kaur, . J. (2023) Age related changes in serum dihydrotestosterone levels among type 2 diabetic males. National Journal of Physiology, Pharmacy and Pharmacology, 13 (7), 1391-1396. doi:10.5455/njppp.2023.13.11537202207122022

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