Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India

Debanjan Roychowdhury; Shyamal Kanti Pal; Brahmarshi Das; Partha Mandal

doi:10.5455/njppp.2023.13.01017202317012023

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Natl J Physiol Pharm Pharmacol. 2023; 13(3): 589-594

doi: 10.5455/njppp.2023.13.01017202317012023

Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India

Debanjan Roychowdhury, Shyamal Kanti Pal, Brahmarshi Das, Partha Mandal.

Abstract
Background: Diabetes mellitus (DM) is an expanding global health problem. Type 2 DM (T2DM) patients account about 90% of total DM patients. Magnesium is important for different physiological mechanism. Hypomagnesemia is common in T2DM patient. Magnitude of hypomagnesemia is related with glycemic control and is associated with complications of T2DM.

Aims and Objectives: Our aim of the study was to assess the prevalence of hypomagnesemia in patients of T2DM patients and to find their correlation with glycemic control and complications of T2DM patients in rural population of eastern zone of India.

Materials and Methods: The hospital-based cross-sectional study includes 99 male and female DM patients between 15 and 60 years age. Fasting blood sugar, postprandial blood sugar, HbA1c, serum total magnesium, and urine albumin creatinine ratio were measured. Data were entered into Microsoft Excel spreadsheet and then analyzed by SPSS (version 25.0; SPSS Inc.) and GraphPad Prism (version 5.0). P < 0.05 was considered statistically significant.

Results: From our study, we observed that hypomagnesemia is common in T2DM patients. The magnitude of hypomagnesemia is correlated with glycemic control (P < 0.0001). Moreover, hypomagnesemia is associated with diabetic kidney diseases (P < 0.05).

Conclusion: It can be concluded that serum magnesium should be monitored in all T2DM patients and should be managed appropriately because hypomagnesemia may induce complications in T2DM patients.

Key words: Diabetes Mellitus; Magnesium; Hypomagnesemia; HbA1c; Urine Albumin Creatinine Ratio

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Pubmed Style

Roychowdhury D, Pal SK, Das B, Mandal P. Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India. Natl J Physiol Pharm Pharmacol. 2023; 13(3): 589-594. doi:10.5455/njppp.2023.13.01017202317012023

Web Style

Roychowdhury D, Pal SK, Das B, Mandal P. Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India. https://www.njppp.com/?mno=138413 [Access: May 03, 2023]. doi:10.5455/njppp.2023.13.01017202317012023

AMA (American Medical Association) Style

Roychowdhury D, Pal SK, Das B, Mandal P. Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India. Natl J Physiol Pharm Pharmacol. 2023; 13(3): 589-594. doi:10.5455/njppp.2023.13.01017202317012023

Vancouver/ICMJE Style

Roychowdhury D, Pal SK, Das B, Mandal P. Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India. Natl J Physiol Pharm Pharmacol. (2023), [cited May 03, 2023]; 13(3): 589-594. doi:10.5455/njppp.2023.13.01017202317012023

Harvard Style

Roychowdhury, D., Pal, . S. K., Das, . B. & Mandal, . P. (2023) Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India. Natl J Physiol Pharm Pharmacol, 13 (3), 589-594. doi:10.5455/njppp.2023.13.01017202317012023

Turabian Style

Roychowdhury, Debanjan, Shyamal Kanti Pal, Brahmarshi Das, and Partha Mandal. 2023. Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India. National Journal of Physiology, Pharmacy and Pharmacology, 13 (3), 589-594. doi:10.5455/njppp.2023.13.01017202317012023

Chicago Style

Roychowdhury, Debanjan, Shyamal Kanti Pal, Brahmarshi Das, and Partha Mandal. "Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 589-594. doi:10.5455/njppp.2023.13.01017202317012023

MLA (The Modern Language Association) Style

Roychowdhury, Debanjan, Shyamal Kanti Pal, Brahmarshi Das, and Partha Mandal. "Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India." National Journal of Physiology, Pharmacy and Pharmacology 13.3 (2023), 589-594. Print. doi:10.5455/njppp.2023.13.01017202317012023

APA (American Psychological Association) Style

Roychowdhury, D., Pal, . S. K., Das, . B. & Mandal, . P. (2023) Assessment of serum magnesium and correlation with glycemic control and complication in type 2 diabetes mellitus – A cross-sectional study in a tertiary care hospital in eastern zone of India. National Journal of Physiology, Pharmacy and Pharmacology, 13 (3), 589-594. doi:10.5455/njppp.2023.13.01017202317012023

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