E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
17 / 02 / 2023

 


Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients

Gajendra Singh Dhakad, Remesh Kunjunni, Arun Mishra.


Abstract
Background: Vitamin D deficiency and associated complications are widely prevalent in the Indian subcontinent. Hypovitaminosis D is known to play deleterious effects on cardiovascular and skeletal functions in human beings. Yet, its effect on carbohydrate metabolism and diabetes mellitus (DM) is less known.

Aim and Objectives: In the current case– control study, our primary aim is to find out the potential effect of hypovitaminosis D on glycemic control in type 2 DM (T2DM) patients.

Materials and Methods: The study population comprised 250 T2DM patients recruited primarily from Madhya Pradesh, India. The case group of 125 T2DM patients with hypovitaminosis D was compared with a control group of 125 T2DM patients with sufficient vitamin D. We mainly investigated the effect of hypovitaminosis D (both deficiency and insufficiency) on glycemic control in T2DM patients.

Results: We observed that both fasting and 2-h postprandial blood glucose were found to be elevated significantly in T2DM patients with hypovitaminosis D (P < 0.01). The glycated hemoglobin level was also elevated (P < 0.01) in the case group suggesting impaired glycemic control for a chronic period. An inverse association is found between glycemic status and serum vitamin D (OH)D3 levels.

Conclusions: Our results show the significance of maintaining sufficient plasma vitamin D levels, along with hypoglycemic medication in T2DM patients to improve their glycemic control and avoid diabetic comorbidities.

Key words: Hypovitaminosis D; Type 2 Diabetes Mellitus; Glycated Hemoglobin; Glycemic Control


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Gajendra Singh Dhakad
Articles by Remesh Kunjunni
Articles by Arun Mishra
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Dhakad GS, Kunjunni R, Mishra A. Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients. Natl J Physiol Pharm Pharmacol. 2023; 13(3): 661-665. doi:10.5455/njppp.2023.13.02068202310022023


Web Style

Dhakad GS, Kunjunni R, Mishra A. Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients. https://www.njppp.com/?mno=143005 [Access: March 15, 2024]. doi:10.5455/njppp.2023.13.02068202310022023


AMA (American Medical Association) Style

Dhakad GS, Kunjunni R, Mishra A. Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients. Natl J Physiol Pharm Pharmacol. 2023; 13(3): 661-665. doi:10.5455/njppp.2023.13.02068202310022023



Vancouver/ICMJE Style

Dhakad GS, Kunjunni R, Mishra A. Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients. Natl J Physiol Pharm Pharmacol. (2023), [cited March 15, 2024]; 13(3): 661-665. doi:10.5455/njppp.2023.13.02068202310022023



Harvard Style

Dhakad, G. S., Kunjunni, . R. & Mishra, . A. (2023) Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients. Natl J Physiol Pharm Pharmacol, 13 (3), 661-665. doi:10.5455/njppp.2023.13.02068202310022023



Turabian Style

Dhakad, Gajendra Singh, Remesh Kunjunni, and Arun Mishra. 2023. Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients. National Journal of Physiology, Pharmacy and Pharmacology, 13 (3), 661-665. doi:10.5455/njppp.2023.13.02068202310022023



Chicago Style

Dhakad, Gajendra Singh, Remesh Kunjunni, and Arun Mishra. "Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 661-665. doi:10.5455/njppp.2023.13.02068202310022023



MLA (The Modern Language Association) Style

Dhakad, Gajendra Singh, Remesh Kunjunni, and Arun Mishra. "Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients." National Journal of Physiology, Pharmacy and Pharmacology 13.3 (2023), 661-665. Print. doi:10.5455/njppp.2023.13.02068202310022023



APA (American Psychological Association) Style

Dhakad, G. S., Kunjunni, . R. & Mishra, . A. (2023) Hypovitaminosis D causes suboptimal glycemic control in type 2 diabetic patients. National Journal of Physiology, Pharmacy and Pharmacology, 13 (3), 661-665. doi:10.5455/njppp.2023.13.02068202310022023