E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research
Online Published: 03 May 2024
 


Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study

Shilpa Pimparkar, Mohankumar Tambe, Nitin Dhokane, Angesh Bagade.


Abstract
Background: Type 2 diabetes mellitus (T2DM) is a common and prevalent metabolic disorder linked to numerous health complications. Recent research has indicated a potential association between T2DM and cognitive impairment, although the underlying mechanisms remain unclear.

Aims and Objectives: This cross-sectional study aimed to investigate neurocognitive functions and information processing ability in T2DM patients compared to healthy individuals.

Materials and Methods: A total of 160 participants, including 80 T2DM patients under medication and 80 age- and sex-matched healthy controls, were enrolled. Cognitive assessments were conducted using Addenbrooke’s cognitive examination (ACE-III) and audiovisual reaction time tests. Statistical analyses were performed to assess differences and correlations between groups.

Results: The study revealed that T2DM patients exhibited delayed neurocognitive functions, including prolonged auditory and visual reaction times, and lower ACE-III scores compared to healthy controls. Notably, a significant positive correlation between HbA1c levels and cognitive impairment was observed in the diabetic group.

Conclusion: This study underscores the presence of cognitive deficits in T2DM patients and highlights the importance of routine cognitive assessment during clinical follow-up. The findings suggest that optimizing glycemic control may offer potential benefits in mitigating cognitive decline in individuals with T2DM. These insights contribute to our understanding of the interplay between T2DM and cognitive function, paving the way for improved patient care and interventions.

Key words: Type 2 Diabetes Mellitus; Neurocognitive Functions; Audiovisual Reaction Times; Addenbrooke’s Cognitive Examination-III


 
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How to Cite this Article
Pubmed Style

Pimparkar S, Tambe M, Dhokane N, Bagade A. Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2024; 14(9): 1967-1970. doi:10.5455/njppp.2024.14.01019202425042024


Web Style

Pimparkar S, Tambe M, Dhokane N, Bagade A. Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study. https://www.njppp.com/?mno=184335 [Access: October 05, 2024]. doi:10.5455/njppp.2024.14.01019202425042024


AMA (American Medical Association) Style

Pimparkar S, Tambe M, Dhokane N, Bagade A. Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2024; 14(9): 1967-1970. doi:10.5455/njppp.2024.14.01019202425042024



Vancouver/ICMJE Style

Pimparkar S, Tambe M, Dhokane N, Bagade A. Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study. Natl J Physiol Pharm Pharmacol. (2024), [cited October 05, 2024]; 14(9): 1967-1970. doi:10.5455/njppp.2024.14.01019202425042024



Harvard Style

Pimparkar, S., Tambe, . M., Dhokane, . N. & Bagade, . A. (2024) Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study. Natl J Physiol Pharm Pharmacol, 14 (9), 1967-1970. doi:10.5455/njppp.2024.14.01019202425042024



Turabian Style

Pimparkar, Shilpa, Mohankumar Tambe, Nitin Dhokane, and Angesh Bagade. 2024. Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (9), 1967-1970. doi:10.5455/njppp.2024.14.01019202425042024



Chicago Style

Pimparkar, Shilpa, Mohankumar Tambe, Nitin Dhokane, and Angesh Bagade. "Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 1967-1970. doi:10.5455/njppp.2024.14.01019202425042024



MLA (The Modern Language Association) Style

Pimparkar, Shilpa, Mohankumar Tambe, Nitin Dhokane, and Angesh Bagade. "Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 14.9 (2024), 1967-1970. Print. doi:10.5455/njppp.2024.14.01019202425042024



APA (American Psychological Association) Style

Pimparkar, S., Tambe, . M., Dhokane, . N. & Bagade, . A. (2024) Assessment of neurocognitive functions and information processing ability among type 2 diabetes mellitus patients in Central India – A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (9), 1967-1970. doi:10.5455/njppp.2024.14.01019202425042024





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