E-ISSN 2231-3206 | ISSN 2320-4672
 
2024, Vol: 14, Issue: 10
14 / 10Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles
Required files to be uploaded

Authorship Declaration

Original Research
Online Published: 21 Aug 2024
 


Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study

Sheveta Dureja, Vikram Bhandari, Rachna Bachhel, Narinder Singh, Jaswinder Singh, Rahat Kumar.


Abstract
Background: There is an increased prevalence of cardiovascular and metabolic diseases in postmenopausal women. Estrogen plays an important role in the regulation of blood pressure (BP) and autonomic function. Various hormone therapies are widely used in postmenopausal women, especially combination therapy of low-dose estrogen and progesterone. Hormone therapy might be useful not only in alleviating menopausal symptoms but help in reducing cardiovascular risk factors and improving quality of life.

Aims and Objectives: The aim of the study is to study the effect of combined estrogen and progesterone hormone therapy on BP and sympathetic overactivity in postmenopausal women.

Materials and Methods: The study included two groups of 50 women each. Group I included postmenopausal women of age 45–55 years who were taking combined hormone therapy while Group II included postmenopausal women of the same age group who were not on any replacement therapy. Heart rate and BP in resting state was noted in both the groups. Sympathetic function assessment was done by performing cold pressor test, handgrip test, and BP response to standing on all the participants. Statistical analysis was done using the student’s t-test.

Results: There was a statistically significant difference in resting heart rate, BP, and sympathetic function tests in both groups.

Conclusion: There is a facilitatory role of combined estrogen and progesterone therapy in menopausal women in reducing BP and sympathetic system dysregulation.

Key words: Menopause; Estrogen; Progesterone; Sympathetic Nervous System Function


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Sheveta Dureja
Articles by Vikram Bhandari
Articles by Rachna Bachhel
Articles by Narinder Singh
Articles by Jaswinder Singh
Articles by Rahat Kumar
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Dureja S, Bhandari V, Bachhel R, Singh N, Singh J, Kumar R. Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2024; 14(9): 1919-1922. doi:10.5455/njppp.2024.13.08334202410082024

Web Style

Dureja S, Bhandari V, Bachhel R, Singh N, Singh J, Kumar R. Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study. https://www.njppp.com/?mno=214930 [Access: October 04, 2024]. doi:10.5455/njppp.2024.13.08334202410082024

AMA (American Medical Association) Style

Dureja S, Bhandari V, Bachhel R, Singh N, Singh J, Kumar R. Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2024; 14(9): 1919-1922. doi:10.5455/njppp.2024.13.08334202410082024


Vancouver/ICMJE Style

Dureja S, Bhandari V, Bachhel R, Singh N, Singh J, Kumar R. Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study. Natl J Physiol Pharm Pharmacol. (2024), [cited October 04, 2024]; 14(9): 1919-1922. doi:10.5455/njppp.2024.13.08334202410082024


Harvard Style

Dureja, S., Bhandari, . V., Bachhel, . R., Singh, . N., Singh, . J. & Kumar, . R. (2024) Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study. Natl J Physiol Pharm Pharmacol, 14 (9), 1919-1922. doi:10.5455/njppp.2024.13.08334202410082024


Turabian Style

Dureja, Sheveta, Vikram Bhandari, Rachna Bachhel, Narinder Singh, Jaswinder Singh, and Rahat Kumar. 2024. Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (9), 1919-1922. doi:10.5455/njppp.2024.13.08334202410082024


Chicago Style

Dureja, Sheveta, Vikram Bhandari, Rachna Bachhel, Narinder Singh, Jaswinder Singh, and Rahat Kumar. "Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 14 (2024), 1919-1922. doi:10.5455/njppp.2024.13.08334202410082024


MLA (The Modern Language Association) Style

Dureja, Sheveta, Vikram Bhandari, Rachna Bachhel, Narinder Singh, Jaswinder Singh, and Rahat Kumar. "Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 14.9 (2024), 1919-1922. Print. doi:10.5455/njppp.2024.13.08334202410082024


APA (American Psychological Association) Style

Dureja, S., Bhandari, . V., Bachhel, . R., Singh, . N., Singh, . J. & Kumar, . R. (2024) Effect of combined hormone replacement therapy on sympathetic nervous system function in postmenopausal women – A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 14 (9), 1919-1922. doi:10.5455/njppp.2024.13.08334202410082024




Most Viewed Articles
Most Accessed Articles

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Assessment of Nutritional Status of Pregnant Women Attending the City Tebessa PMI (Algeria) [English]
    Taleb Salima, Kaibi Mounira, Deghboudj Nadjia
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 97-105
    » Abstract

  • Difference in pulmonary function test among the athletic and sedentary population
    ShobhaRani Vedala, Niranjan Paul, Abhay B Mane
    Natl J Physiol Pharm Pharmacol. 2013; 3(2): 118-123
    » Abstract » doi: 10.5455/njppp.2013.3.109-114

    •
    Most Downloaded
    Top Downloaded Articles

  • How to calculate sample size in animal studies?
    Hitesh Shah
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 35-39
    » Abstract

  • Applications of computer science in Pharmacy: An overview
    Shivraj Popat Jadhav, Komal Nikam, Anand Gandhi, Kishor Salunkhe, Narendra Shinde.
    Natl J Physiol Pharm Pharmacol. 2012; 2(1): 1-9
    » Abstract

  • Evaluation of potential drug-drug interaction in indoor patients of pediatric department of tertiary care hospital
    Simran Patel, Mayur Chaudhari, Nrupal Patel
    Natl J Physiol Pharm Pharmacol. 2019; 9(10): 1012-1016
    » Abstract » doi: 10.5455/njppp.2019.9.0725209072019

  • Chlorhexidine:The gold standard in chemical plaque control [English]
    Setu mathur, Tanu mathur,Rahul shrivastava, Rohit khatri
    Natl J Physiol Pharm Pharmacol. 2011; 1(2): 45-50
    » Abstract

  • Analyzing Pharmaceutical Industry [English]
    Veselin Tima Dickov, Dragan Mitrovic, Boris Milan Kuzman
    Natl J Physiol Pharm Pharmacol. 2011; 1(1): 1-8
    » Abstract » doi: 10.5455/njppp.2011.1.1-8

    •
    Most Cited Articles
    Most Cited Articles

    About National Journal of Physiology, Pharmacy and Pharmacology

      National Journal of Physiology, Pharmacy and Pharmacology is a monthly peer reviewed journal.  The journal is having open access polic ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Eldaghayes Publisher

    www.eldagpublisher.com 

     
    All correspondence should be addressed to:
    Prof. Ibrahim Eldaghayes
    Editor-in-Chief
    National Journal of Physiology, Pharmacy and Pharmacology
    Email: ibrahim.eldaghayes@vetmed.edu.ly
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Copyright Information
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Open Access Policy
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use