E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
25 / 05 / 2016

 


Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma

Eman Elsharkawy.


Abstract
Background: At present, there are considerable scientific evidences to suggest that nutritive and non-nutritive plant-based dietary factors can inhibit the process of carcinogenesis effectively.

Aims and Objective: The aim of the present study was to use essential oils extracted by different methods from Achillea fragrantissima (hexane extract [HE] and oil extract [OE]) in the manufacture of soap, which can be used as anti-inflammatory agent.

Materials and Methods: The anti-inflammatory effect of volatile oil was studied using carrageenan induced paw edema method at 100 mg/kg dose orally. Furthermore, it also studies the chemical composition of Achillea extracts by GC-MS.

Results: This study demonstrated that extracts of Achillea fragrantissima have excellent anti-inflammatory properties. Of the two extracts analyzed by gas chromatographymass spectrometry (GC-MS), there were differences in the chemical composition of essential oil of two extracts. Bisabolol, bisabolol oxide, menthol, and b-caryophyllene are the major constituents of the Achillea extract, some compounds were found in OE and not found in HE. Conclusion: Our observations supports Achillea fragrantissima which is used by many
people in the northern region for medicinal uses, it is safe and it can be used as anti-inflammatory drug.

Key words: Anti-inflammatory; Natural Soap; Achillea fragrantissima


 
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Pubmed Style

Eman Elsharkawy. Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma. Natl J Physiol Pharm Pharmacol. 2016; 6(3): 258-262. doi:10.5455/njppp.2016.6.23022016130


Web Style

Eman Elsharkawy. Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma. https://www.njppp.com/?mno=219604 [Access: March 15, 2024]. doi:10.5455/njppp.2016.6.23022016130


AMA (American Medical Association) Style

Eman Elsharkawy. Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma. Natl J Physiol Pharm Pharmacol. 2016; 6(3): 258-262. doi:10.5455/njppp.2016.6.23022016130



Vancouver/ICMJE Style

Eman Elsharkawy. Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma. Natl J Physiol Pharm Pharmacol. (2016), [cited March 15, 2024]; 6(3): 258-262. doi:10.5455/njppp.2016.6.23022016130



Harvard Style

Eman Elsharkawy (2016) Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma. Natl J Physiol Pharm Pharmacol, 6 (3), 258-262. doi:10.5455/njppp.2016.6.23022016130



Turabian Style

Eman Elsharkawy. 2016. Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma. National Journal of Physiology, Pharmacy and Pharmacology, 6 (3), 258-262. doi:10.5455/njppp.2016.6.23022016130



Chicago Style

Eman Elsharkawy. "Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 258-262. doi:10.5455/njppp.2016.6.23022016130



MLA (The Modern Language Association) Style

Eman Elsharkawy. "Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma." National Journal of Physiology, Pharmacy and Pharmacology 6.3 (2016), 258-262. Print. doi:10.5455/njppp.2016.6.23022016130



APA (American Psychological Association) Style

Eman Elsharkawy (2016) Anti-inflammatory activity and chemical compositions of essential oil of Achillea fragmmentissma. National Journal of Physiology, Pharmacy and Pharmacology, 6 (3), 258-262. doi:10.5455/njppp.2016.6.23022016130