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Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva.

Abstract
Background: The paper presents data on the structure and the function of erythrocyte membranes in moderate degree iron-deficiency anemia (IDA) in early-age children living in mountain conditions.

Aim and Objectives: Explore pathogenic mechanisms for membrane destructive disorders in IDA in the early-age children living in the high-mountain area and develop a program for diagnostics and reasonable kinds of etiopathogenetic therapy.

Materials and Methods: Research was made in high-mountain regions of the Kyrgyz Republic. A clinical supervision was made in dynamics with a focus on a structure of peripheral blood, maintained phospholipids fractions detected in erythrocytes membranes with a method of thin-layer chromatography on Silufol plates and with a quantitative definition of phosphorus by Barlet’s method.

Result: In IDA in children in the mountain area, there is a disorder in phospholipids between blood plasma and red blood cells with an accumulation of the lizoform.

Conclusion: The paper presents the findings that relate to pathogenic mechanisms for disorders in the phospholipid composition of erythrocytes membranes in moderate degree IDA among 170 early-age children living in the high mountains zone in the Kyrgyz Republic. The paper also includes the indicators and presents results saying of a positive dynamic in specific membrane phospholipids of erythrocyte disorders liquidation in the treatment with a preparation of iron sulfate with folic acid.

Key words: Early-age Children; Erythrocytes; Iron-deficiency Anemia; High Mountains


 
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How to Cite this Article
Pubmed Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 445-448. doi:10.5455/njppp.2016.6.0512610062016


Web Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. https://www.njppp.com/?mno=228174 [Access: December 01, 2022]. doi:10.5455/njppp.2016.6.0512610062016


AMA (American Medical Association) Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. Natl J Physiol Pharm Pharmacol. 2016; 6(5): 445-448. doi:10.5455/njppp.2016.6.0512610062016



Vancouver/ICMJE Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. Natl J Physiol Pharm Pharmacol. (2016), [cited December 01, 2022]; 6(5): 445-448. doi:10.5455/njppp.2016.6.0512610062016



Harvard Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva (2016) Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. Natl J Physiol Pharm Pharmacol, 6 (5), 445-448. doi:10.5455/njppp.2016.6.0512610062016



Turabian Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva. 2016. Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 445-448. doi:10.5455/njppp.2016.6.0512610062016



Chicago Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva. "Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 445-448. doi:10.5455/njppp.2016.6.0512610062016



MLA (The Modern Language Association) Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva. "Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions." National Journal of Physiology, Pharmacy and Pharmacology 6.5 (2016), 445-448. Print. doi:10.5455/njppp.2016.6.0512610062016



APA (American Psychological Association) Style

Asankul A. Kucherbaev, Jury V. Borjakin, Kubat S. Ibraimov, Aigul B. Cherikchieva (2016) Structure and function of erythrocyte membranes in moderate degree iron-deficiency anemia in early-age children in mountain conditions. National Journal of Physiology, Pharmacy and Pharmacology, 6 (5), 445-448. doi:10.5455/njppp.2016.6.0512610062016