E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


The anxiolytic effect of bee pollen hydroalcoholic extract in mice

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir.

Cited by (3)

Abstract
Background: Anxiety is a common human mental disorder. Medicinal therapy of this disease is associated with many side-effects. Thus, search for new medication with fewer side-effects seems inevitable. Bee pollen (often referred to as a life-giving dust) has various therapeutic properties.

Aims and Objectives: In this study, potential anxiolytic effects of hydroalcoholic extract of bee pollen was examined in mice.

Materials and Methods: This study was conducted on 20-25 g male mice in three groups of eight. Animals received intraperitoneal injections of hydroalcoholic extract of bee pollen at 200, 400, 800, and 1600 mg/kg doses, diazepam at 1 mg/kg dose, and saline at 10 ml/kg dose. 30 min after injection, animals were studied in elevated plus maze device for 5 min.

Results: The results obtained showed significantly longer presence in open arms of elevated plus maze device of animals that received 800 and 1600 mg/kg doses of hydroalcoholic extract of bee pollen compared to animals that received diazepam. However, no significant difference was observed between 1600 and 800 mg/kg doses.

Conclusion: The above results confirmed anxiolytic effect of hydroalcoholic extract of bee pollen on mice.

Key words: Bee Pollen; Anxiety; Elevated Plus Maze; Mice


 
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How to Cite this Article
Pubmed Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir. The anxiolytic effect of bee pollen hydroalcoholic extract in mice. Natl J Physiol Pharm Pharmacol. 2017; 7(3): 301-305. doi:10.5455/njppp.2017.7.0617914112016


Web Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir. The anxiolytic effect of bee pollen hydroalcoholic extract in mice. https://www.njppp.com/?mno=234318 [Access: January 03, 2023]. doi:10.5455/njppp.2017.7.0617914112016


AMA (American Medical Association) Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir. The anxiolytic effect of bee pollen hydroalcoholic extract in mice. Natl J Physiol Pharm Pharmacol. 2017; 7(3): 301-305. doi:10.5455/njppp.2017.7.0617914112016



Vancouver/ICMJE Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir. The anxiolytic effect of bee pollen hydroalcoholic extract in mice. Natl J Physiol Pharm Pharmacol. (2017), [cited January 03, 2023]; 7(3): 301-305. doi:10.5455/njppp.2017.7.0617914112016



Harvard Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir (2017) The anxiolytic effect of bee pollen hydroalcoholic extract in mice. Natl J Physiol Pharm Pharmacol, 7 (3), 301-305. doi:10.5455/njppp.2017.7.0617914112016



Turabian Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir. 2017. The anxiolytic effect of bee pollen hydroalcoholic extract in mice. National Journal of Physiology, Pharmacy and Pharmacology, 7 (3), 301-305. doi:10.5455/njppp.2017.7.0617914112016



Chicago Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir. "The anxiolytic effect of bee pollen hydroalcoholic extract in mice." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 301-305. doi:10.5455/njppp.2017.7.0617914112016



MLA (The Modern Language Association) Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir. "The anxiolytic effect of bee pollen hydroalcoholic extract in mice." National Journal of Physiology, Pharmacy and Pharmacology 7.3 (2017), 301-305. Print. doi:10.5455/njppp.2017.7.0617914112016



APA (American Psychological Association) Style

Neda Sistani Karampour, Ali Asghar Hemmati, Azam Malmir (2017) The anxiolytic effect of bee pollen hydroalcoholic extract in mice. National Journal of Physiology, Pharmacy and Pharmacology, 7 (3), 301-305. doi:10.5455/njppp.2017.7.0617914112016