Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis

Scandashree K; Praveen Kumar B; Padmaja Udaykumar; Meghana Patil

doi:10.5455/njppp.2017.7.0823919082016

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Online Published: 30 Aug 2016

Natl J Physiol Pharm Pharmacol. 2017; 7(2): 147-150

doi: 10.5455/njppp.2017.7.0823919082016

Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil.

Abstract
Background: Olopatadine hydrochloride is one of the most promising agents with a broad range of pharmacological effects. It has both antihistaminic and mast cell stabilizing properties. It is used in various allergic diseases, and its ophthalmic solution is used in allergic conjunctivitis.

Aims and Objectives: To assess the clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis.

Materials and Methods: This was a prospective interventional study conducted to assess the clinical efficacy and safety of 0.2% olopatadine hydrochloride ophthalmic solution on 49 pediatric allergic conjunctivitis patients. 1-2 drops of the ophthalmic solution were administered once daily in each eye for 6 weeks. Scoring of redness, itching, watering, and photophobia was estimated at baseline, 2 week and 6 weeks. Adverse effects were noted at each visit if any.

Results: The mean scores of redness, itching, watering, and photophobia were reduced after 2 weeks of treatment which was statistically significant (P < 0.001).

Conclusion: Olopatadine hydrochloride 0.2% once daily administration was effective in reducing ocular signs and symptoms in allergic conjunctivitis in the pediatric population.

Key words: Olopatadine; Allergic Conjunctivitis; Children; Effectiveness

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Pubmed Style

K S, B PK, Udaykumar P, Patil M. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Natl J Physiol Pharm Pharmacol. 2017; 7(2): 147-150. doi:10.5455/njppp.2017.7.0823919082016

Web Style

K S, B PK, Udaykumar P, Patil M. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. https://www.njppp.com/?mno=239684 [Access: June 27, 2026]. doi:10.5455/njppp.2017.7.0823919082016

AMA (American Medical Association) Style

K S, B PK, Udaykumar P, Patil M. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Natl J Physiol Pharm Pharmacol. 2017; 7(2): 147-150. doi:10.5455/njppp.2017.7.0823919082016

Vancouver/ICMJE Style

K S, B PK, Udaykumar P, Patil M. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Natl J Physiol Pharm Pharmacol. (2017), [cited June 27, 2026]; 7(2): 147-150. doi:10.5455/njppp.2017.7.0823919082016

Harvard Style

K, S., B, . P. K., Udaykumar, . P. & Patil, . M. (2017) Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Natl J Physiol Pharm Pharmacol, 7 (2), 147-150. doi:10.5455/njppp.2017.7.0823919082016

Turabian Style

K, Scandashree, Praveen Kumar B, Padmaja Udaykumar, and Meghana Patil. 2017. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (2), 147-150. doi:10.5455/njppp.2017.7.0823919082016

Chicago Style

K, Scandashree, Praveen Kumar B, Padmaja Udaykumar, and Meghana Patil. "Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 147-150. doi:10.5455/njppp.2017.7.0823919082016

MLA (The Modern Language Association) Style

K, Scandashree, Praveen Kumar B, Padmaja Udaykumar, and Meghana Patil. "Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis." National Journal of Physiology, Pharmacy and Pharmacology 7.2 (2017), 147-150. Print. doi:10.5455/njppp.2017.7.0823919082016

APA (American Psychological Association) Style

K, S., B, . P. K., Udaykumar, . P. & Patil, . M. (2017) Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (2), 147-150. doi:10.5455/njppp.2017.7.0823919082016

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