E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil.

Abstract
Background: Olopatadine hydrochloride is one of the most promising agents with a broad range of pharmacological effects. It has both antihistaminic and mast cell stabilizing properties. It is used in various allergic diseases, and its ophthalmic solution is used in allergic conjunctivitis.

Aims and Objectives: To assess the clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis.

Materials and Methods: This was a prospective interventional study conducted to assess the clinical efficacy and safety of 0.2% olopatadine hydrochloride ophthalmic solution on 49 pediatric allergic conjunctivitis patients. 1-2 drops of the ophthalmic solution were administered once daily in each eye for 6 weeks. Scoring of redness, itching, watering, and photophobia was estimated at baseline, 2 week and 6 weeks. Adverse effects were noted at each visit if any.

Results: The mean scores of redness, itching, watering, and photophobia were reduced after 2 weeks of treatment which was statistically significant (P < 0.001).

Conclusion: Olopatadine hydrochloride 0.2% once daily administration was effective in reducing ocular signs and symptoms in allergic conjunctivitis in the pediatric population.

Key words: Olopatadine; Allergic Conjunctivitis; Children; Effectiveness


 
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How to Cite this Article
Pubmed Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Natl J Physiol Pharm Pharmacol. 2017; 7(2): 147-150. doi:10.5455/njppp.2017.7.0823919082016


Web Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. https://www.njppp.com/?mno=239684 [Access: December 01, 2022]. doi:10.5455/njppp.2017.7.0823919082016


AMA (American Medical Association) Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Natl J Physiol Pharm Pharmacol. 2017; 7(2): 147-150. doi:10.5455/njppp.2017.7.0823919082016



Vancouver/ICMJE Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Natl J Physiol Pharm Pharmacol. (2017), [cited December 01, 2022]; 7(2): 147-150. doi:10.5455/njppp.2017.7.0823919082016



Harvard Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil (2017) Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Natl J Physiol Pharm Pharmacol, 7 (2), 147-150. doi:10.5455/njppp.2017.7.0823919082016



Turabian Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil. 2017. Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (2), 147-150. doi:10.5455/njppp.2017.7.0823919082016



Chicago Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil. "Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 147-150. doi:10.5455/njppp.2017.7.0823919082016



MLA (The Modern Language Association) Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil. "Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis." National Journal of Physiology, Pharmacy and Pharmacology 7.2 (2017), 147-150. Print. doi:10.5455/njppp.2017.7.0823919082016



APA (American Psychological Association) Style

Scandashree K, Praveen Kumar B, Padmaja Udaykumar, Meghana Patil (2017) Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. National Journal of Physiology, Pharmacy and Pharmacology, 7 (2), 147-150. doi:10.5455/njppp.2017.7.0823919082016