E-ISSN 2231-3206 | ISSN 2320-4672
 
2026, Vol: 16, Issue: 1
16 / 1Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

NJPPP Manuscript Submission Form
Title Page

Original Research
Online Published: 11 Jan 2017
 


Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice

Parvathy Velayudhan Nair, Bindulatha Nair.


Cited By:9

Abstract
Background: Mimosa pudica is a traditionally used folk medicine to treat various disorders such as bleeding disorders, dysentery, piles, convulsions, rheumatoid arthritis, muscular pain, and snake bite.

Aims and Objectives: To evaluate the muscle relaxant activity of hydroalcoholic extract of M. pudica whole plant (HAEMPWP) in albino mice.

Materials and Methods: HAEMPWP was prepared using Soxhlet apparatus. Acute toxicity tests were done using the extract which was given orally to albino mice in increasing doses up to 3200 mg/kg body weight. For pharmacological study, the extract in doses of 200, 400, and 800 mg/kg was orally administered to albino mice. The muscle relaxant action was evaluated by Chimney test and Rotarod method. Data analysis was done by unpaired t-test, one-way ANOVA, Chi-square test, and log-probit analysis using SPSS software version 16.

Results: HAEMPWP showed a significant dose-dependent increase in muscle relaxant activity as compared to control.

Conclusion: HAEMPWP possesses significant muscle relaxant activity and could be an effective treatment option for various spasmodic conditions.

Key words: Mimosa pudica; Muscle Relaxant; Rotarod; Chimney Test; Soxhlet Apparatus


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Parvathy Velayudhan Nair
Articles by Bindulatha Nair
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Nair PV, Nair B. Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice. Natl J Physiol Pharm Pharmacol. 2017; 7(4): 432-437. doi:10.5455/njppp.2017.7.1235704012017

Web Style

Nair PV, Nair B. Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice. https://www.njppp.com/?mno=253618 [Access: June 26, 2026]. doi:10.5455/njppp.2017.7.1235704012017

AMA (American Medical Association) Style

Nair PV, Nair B. Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice. Natl J Physiol Pharm Pharmacol. 2017; 7(4): 432-437. doi:10.5455/njppp.2017.7.1235704012017


Vancouver/ICMJE Style

Nair PV, Nair B. Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice. Natl J Physiol Pharm Pharmacol. (2017), [cited June 26, 2026]; 7(4): 432-437. doi:10.5455/njppp.2017.7.1235704012017


Harvard Style

Nair, P. V. & Nair, . B. (2017) Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice. Natl J Physiol Pharm Pharmacol, 7 (4), 432-437. doi:10.5455/njppp.2017.7.1235704012017


Turabian Style

Nair, Parvathy Velayudhan, and Bindulatha Nair. 2017. Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice. National Journal of Physiology, Pharmacy and Pharmacology, 7 (4), 432-437. doi:10.5455/njppp.2017.7.1235704012017


Chicago Style

Nair, Parvathy Velayudhan, and Bindulatha Nair. "Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 432-437. doi:10.5455/njppp.2017.7.1235704012017


MLA (The Modern Language Association) Style

Nair, Parvathy Velayudhan, and Bindulatha Nair. "Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice." National Journal of Physiology, Pharmacy and Pharmacology 7.4 (2017), 432-437. Print. doi:10.5455/njppp.2017.7.1235704012017


APA (American Psychological Association) Style

Nair, P. V. & Nair, . B. (2017) Muscle relaxant activity of hydroalcoholic extract of Mimosa pudica whole plant in mice. National Journal of Physiology, Pharmacy and Pharmacology, 7 (4), 432-437. doi:10.5455/njppp.2017.7.1235704012017


Author LoginReviewer LoginAbout PublisherOpen Access PolicyEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesDigital Archiving & Preservation PoliciesStatement of Informed ConsentAdvertising PolicyTerms of UseLicense InformationCopyright Information

About National Journal of Physiology, Pharmacy and Pharmacology

About the JournalThe National Journal of Physiology, Pharmacy and Pharmacology (NJPPP) is a peer-reviewed, open-access journal dedicated to advancing rese ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

Eldaghayes Publisher

www.eldaghayes.com 
 

All correspondence should be addressed to:

National Journal of Physiology, Pharmacy and Pharmacology

Email: info@eldaghayes.com