Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study

Arun Chutani; Sonali Pande

doi:10.5455/njppp.2017.7.0515606052017

2023, Vol: 13, Issue: 3

13/3Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Required files to be uploaded

Authorship Declaration

« Previous Article

Original Research

Natl J Physiol Pharm Pharmacol. 2017; 7(9): 914-919

doi: 10.5455/njppp.2017.7.0515606052017

Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study

Arun Chutani, Sonali Pande.

Cited By: 9

Abstract
Background: Diabetes is a common cause of end-stage renal disease and nephropathy, which is characterized by abnormal renal function with reduction of glomerular filtration and rise in the level of serum urea and creatinine.

Aims and Objectives: The aim of this study was to compare serum urea and creatinine levels in Type 1 and Type 2 diabetics and further correlate the serum creatinine and urea levels in both Type 1 and Type 2 diabetic subjects with duration of diabetes and glycosylated hemoglobin levels (HbA1c).

Materials and Methods: Blood samples were collected and analyzed for serum urea and creatinine levels in diabetic subjects, both Type 1 and Type 2 attending diabetic clinic and non-diabetic subjects in a tertiary hospital. 72 male subjects in each group of age 35-55 years were selected for the study. Fasting, post-meal blood sugar levels, and HbA1c of all the subjects in the study were determined. Results were interpreted by one-way analysis of variance test. Association of serum urea and creatinine levels with HbA1c and duration of illness in all diabetic subjects was analyzed by applying Pearsons correlation coefficient.

Results: There was statistically significant increase in serum urea and creatinine levels in both Type 1 and Type 2 diabetic subjects compared to non-diabetic subjects. There was a correlation of levels of serum urea and creatinine with HbA1c levels and duration of diabetes in Type 1 diabetics but not with Type 2 diabetic study group.

Conclusion: Serum urea and creatinine are simple and useful biomarkers which can serve as predictor tests for assessing kidney functions (nephropathy) in diabetic patients.

Key words: Blood Urea; Creatinine; Type 1 Diabetes; Type 2 Diabetes; Nephropathy; Glycosylated Hemoglobin

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Arun Chutani Articles by Sonali Pande
	on Google
	on Google Scholar

This Article Cited By the following articles

Fuzzy logicâbased clinical decision support system for the evaluation of renal function in postâTransplant Patients J Eval Clin Pract 2019; (): .	1

Evaluation of some oxidative markers in diabetes and diabetic retinopathy Diabetol Int 2021; 12(1): 108.	2

Fuzzy logicâbased clinical decision support system for the evaluation of renal function in postâTransplant Patients J Eval Clin Pract 2020; 26(4): 1224.	3

A Preliminary Study Showing the Impact of Genetic and Dietary Factors on GCâMS-Based Plasma Metabolome of Patients with and without PROX1-Genetic Predisposition to T2DM up to 5 Years Prior to Prediabetes Appearance CIMB 2021; 43(2): 513.	4

Quantification of sweat urea in diabetes using electro-optical technique Physiol. Meas. 2021; 42(9): 095002.	5

Leaf Extracts of Anchomanes difformis Ameliorated Kidney and Pancreatic Damage in Type 2 Diabetes Plants 2021; 10(2): 300.	6

Anti-Diabetic Effects of Allium hookeri Extracts Prepared by Different Methods in Type 2 C57BL/J-db/db Mice Pharmaceuticals 2022; 15(4): 486.	7

PPARɣ2, aldose reductase, and TCF7L2 gene polymorphisms: relation to diabetes mellitus J Diabetes Metab Disord 2022; (): .	8

A study on evaluating blood urea and serum creatinine in diabetes mellitus patients IJCBR 2022; 8(4): 285.	9

How to Cite this Article

Pubmed Style

Arun Chutani, Sonali Pande. Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 914-919. doi:10.5455/njppp.2017.7.0515606052017

Web Style

Arun Chutani, Sonali Pande. Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study. https://www.njppp.com/?mno=266080 [Access: March 01, 2023]. doi:10.5455/njppp.2017.7.0515606052017

AMA (American Medical Association) Style

Arun Chutani, Sonali Pande. Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study. Natl J Physiol Pharm Pharmacol. 2017; 7(9): 914-919. doi:10.5455/njppp.2017.7.0515606052017

Vancouver/ICMJE Style

Arun Chutani, Sonali Pande. Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study. Natl J Physiol Pharm Pharmacol. (2017), [cited March 01, 2023]; 7(9): 914-919. doi:10.5455/njppp.2017.7.0515606052017

Harvard Style

Arun Chutani, Sonali Pande (2017) Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study. Natl J Physiol Pharm Pharmacol, 7 (9), 914-919. doi:10.5455/njppp.2017.7.0515606052017

Turabian Style

Arun Chutani, Sonali Pande. 2017. Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 914-919. doi:10.5455/njppp.2017.7.0515606052017

Chicago Style

Arun Chutani, Sonali Pande. "Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 914-919. doi:10.5455/njppp.2017.7.0515606052017

MLA (The Modern Language Association) Style

Arun Chutani, Sonali Pande. "Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study." National Journal of Physiology, Pharmacy and Pharmacology 7.9 (2017), 914-919. Print. doi:10.5455/njppp.2017.7.0515606052017

APA (American Psychological Association) Style

Arun Chutani, Sonali Pande (2017) Correlation of serum creatinine and urea with glycemic index and duration of diabetes in Type 1 and Type 2 diabetes mellitus: A comparative study. National Journal of Physiology, Pharmacy and Pharmacology, 7 (9), 914-919. doi:10.5455/njppp.2017.7.0515606052017

Author Login Reviewer Login About Publisher Editorial Policies Peer Review Policy Editorial & Peer Review Process Publication Ethics and Publication Malpractice Statement Conflict of Interest Policy Plagiarism Policy Protection of Research Participants (Statement On Human And Animal Rights)Corrections, Retractions & Expressions of Concern Self-Archiving Policies Statement of Informed Consent Advertising Policy Terms of Use License Information Copyright Information



Copyright © 2023 National Journal of Physiology, Pharmacy and Pharmacology All Rights Reserved. Subject to change without notice from or liability to National Journal of Physiology, Pharmacy and Pharmacology. For best results, please use Internet Explorer or Google Chrome	Contact Information Publisher publishernjppp@gmail.com Editorial query editornjppp1@gmail.com MOB - 8780040272

Contact Information

How to cite this article