Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report

Vishnu Manohar; Shilpa Raj; Sreekrishnan T P; Gireesh Kumar K P

doi:10.5455/njppp.2018.8.0728118082017

2026, Vol: 16, Issue: 1

16 / 1Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Required files to be uploaded

NJPPP Manuscript Submission Form
Title Page

« Previous Article

Case Report
Online Published: 13 Sep 2017

Natl J Physiol Pharm Pharmacol. 2018; 8(2): 297-299

doi: 10.5455/njppp.2018.8.0728118082017

Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report

Vishnu Manohar, Shilpa Raj, Sreekrishnan T P, Gireesh Kumar K P.

Cited By:5

Abstract
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Cytokine hemoadsorption is found to be effective in the management of septic shock, by reducing cytokines and other inflammatory mediators, thereby improving hemodynamics and preventing multiple organ dysfunction syndrome. Here, we report a case of 22-year-old male patient, presented with fever, vomiting, loose stools, and altered mental status since 2 weeks, was provisionally diagnosed with severe sepsis/septic shock - salmonella-induced, hepatitis B-induced acute liver failure, hemophagocytic lymphohistiocytosis, and disseminated intravascular coagulopathy. The patient was admitted in intensive care unit and started on cytokine hemoperfusion therapy for 12 h. Before cytokine hemoadsorption, he was on three inotropic supports, IV antibiotics, and other supportive measures. The patient improved symptomatically and hemodynamically within 8 h of cytokine therapy, and inotropic supports were weaned off. Here, we report a successful outcome in a case of septic shock with organ damage treated with cytokine hemoadsorbant as an adjuvant along with routine conservative management.

Key words: Severe Sepsis; Septic Shock; Cytokine Hemoadsorption; Multi-organ Dysfunction; Hemophagocytic Lymphohistiocytosis

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Vishnu Manohar Articles by Shilpa Raj Articles by Sreekrishnan T P Articles by Gireesh Kumar K P
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Manohar V, Raj S, P ST, P GKK. Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report. Natl J Physiol Pharm Pharmacol. 2018; 8(2): 297-299. doi:10.5455/njppp.2018.8.0728118082017

Web Style

Manohar V, Raj S, P ST, P GKK. Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report. https://www.njppp.com/?mno=273350 [Access: June 22, 2026]. doi:10.5455/njppp.2018.8.0728118082017

AMA (American Medical Association) Style

Manohar V, Raj S, P ST, P GKK. Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report. Natl J Physiol Pharm Pharmacol. 2018; 8(2): 297-299. doi:10.5455/njppp.2018.8.0728118082017

Vancouver/ICMJE Style

Manohar V, Raj S, P ST, P GKK. Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report. Natl J Physiol Pharm Pharmacol. (2018), [cited June 22, 2026]; 8(2): 297-299. doi:10.5455/njppp.2018.8.0728118082017

Harvard Style

Manohar, V., Raj, . S., P, . S. T. & P, . G. K. K. (2018) Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report. Natl J Physiol Pharm Pharmacol, 8 (2), 297-299. doi:10.5455/njppp.2018.8.0728118082017

Turabian Style

Manohar, Vishnu, Shilpa Raj, Sreekrishnan T P, and Gireesh Kumar K P. 2018. Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 8 (2), 297-299. doi:10.5455/njppp.2018.8.0728118082017

Chicago Style

Manohar, Vishnu, Shilpa Raj, Sreekrishnan T P, and Gireesh Kumar K P. "Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 297-299. doi:10.5455/njppp.2018.8.0728118082017

MLA (The Modern Language Association) Style

Manohar, Vishnu, Shilpa Raj, Sreekrishnan T P, and Gireesh Kumar K P. "Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report." National Journal of Physiology, Pharmacy and Pharmacology 8.2 (2018), 297-299. Print. doi:10.5455/njppp.2018.8.0728118082017

APA (American Psychological Association) Style

Manohar, V., Raj, . S., P, . S. T. & P, . G. K. K. (2018) Cytokine hemoadsorption therapy - An adjuvant in the management of septic shock with multi-organ dysfunction: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 8 (2), 297-299. doi:10.5455/njppp.2018.8.0728118082017

About National Journal of Physiology, Pharmacy and Pharmacology

Contact Information

How to cite this article