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Case Report
Online Published: 08 Dec 2017
 


Dapsone hypersensitivity syndrome - A case report

Selvalaxmi Gnanasegaran, Mangaiarkkarasi Adhimoolam, Srija Gopal.


Abstract
Dapsone is widely used for the treatment of leprosy and other immunological and inflammatory dermatological conditions such as dermatitis herpetiformis, vesiculobullous dermatoses, and pustular psoriasis. Dapsone hypersensitivity syndrome (DHS) is a rare reaction associated with fever, skin eruptions, and internal organs involvement. We report a case of DHS who presented with fever, productive cough, dyspnea, skin rashes, and jaundice. Leukocytosis, eosinophilia, and altered liver enzymes were observed in laboratory investigations and patient improved with conservative management.

Key words: Dapsone Hypersensitivity Syndrome; Fever; Skin Eruptions; Leprosy


 
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How to Cite this Article
Pubmed Style

Gnanasegaran S, Adhimoolam M, Gopal S. Dapsone hypersensitivity syndrome - A case report. Natl J Physiol Pharm Pharmacol. 2018; 8(4): 616-618. doi:10.5455/njppp.2017.7.1042308112017

Web Style

Gnanasegaran S, Adhimoolam M, Gopal S. Dapsone hypersensitivity syndrome - A case report. https://www.njppp.com/?mno=281917 [Access: June 27, 2026]. doi:10.5455/njppp.2017.7.1042308112017

AMA (American Medical Association) Style

Gnanasegaran S, Adhimoolam M, Gopal S. Dapsone hypersensitivity syndrome - A case report. Natl J Physiol Pharm Pharmacol. 2018; 8(4): 616-618. doi:10.5455/njppp.2017.7.1042308112017


Vancouver/ICMJE Style

Gnanasegaran S, Adhimoolam M, Gopal S. Dapsone hypersensitivity syndrome - A case report. Natl J Physiol Pharm Pharmacol. (2018), [cited June 27, 2026]; 8(4): 616-618. doi:10.5455/njppp.2017.7.1042308112017


Harvard Style

Gnanasegaran, S., Adhimoolam, . M. & Gopal, . S. (2018) Dapsone hypersensitivity syndrome - A case report. Natl J Physiol Pharm Pharmacol, 8 (4), 616-618. doi:10.5455/njppp.2017.7.1042308112017


Turabian Style

Gnanasegaran, Selvalaxmi, Mangaiarkkarasi Adhimoolam, and Srija Gopal. 2018. Dapsone hypersensitivity syndrome - A case report. National Journal of Physiology, Pharmacy and Pharmacology, 8 (4), 616-618. doi:10.5455/njppp.2017.7.1042308112017


Chicago Style

Gnanasegaran, Selvalaxmi, Mangaiarkkarasi Adhimoolam, and Srija Gopal. "Dapsone hypersensitivity syndrome - A case report." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 616-618. doi:10.5455/njppp.2017.7.1042308112017


MLA (The Modern Language Association) Style

Gnanasegaran, Selvalaxmi, Mangaiarkkarasi Adhimoolam, and Srija Gopal. "Dapsone hypersensitivity syndrome - A case report." National Journal of Physiology, Pharmacy and Pharmacology 8.4 (2018), 616-618. Print. doi:10.5455/njppp.2017.7.1042308112017


APA (American Psychological Association) Style

Gnanasegaran, S., Adhimoolam, . M. & Gopal, . S. (2018) Dapsone hypersensitivity syndrome - A case report. National Journal of Physiology, Pharmacy and Pharmacology, 8 (4), 616-618. doi:10.5455/njppp.2017.7.1042308112017


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