E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia.

Abstract
Background: Streptococcus mutans is known as primary microorganism in the formation of dental plaque and tooth decay.

Aims and Objectives: To determine the antibacterial activity of ant-nest plant ethanol extract to inhibit S. mutans clinical isolates growth in vitro.

Materials and Methods: The ethanol extracts obtained from the ant-nest plant were studied for antibacterial activity against cariogenic S. mutans obtained from patients with clinically identified carious lesions, using the agar diffusion method. Chlorhexidine gluconate was using as a comparative drug. The simplisia of ant-nest plant was extracted using a maceration method. The phytochemical screening was taken using standard methods. The minimum inhibitory concentration (MIC) test was performed by a macrodilution method and following by subculturing the overnight result onto the surface of agar media.

Results: Phytochemical screening of ant-nest plant ethanol extract revealed the presence of polyphenols, flavonoids, tannins, and saponins. The extract showed intensive activity and totally inhibited the growth of S. mutans clinical isolates at 1.25% w/v. In comparison, the chlorhexidine gluconate, essential oil of plants and povidone-iodine in a ranged tested concentration also had given inhibition effect to all hyaluronic acid resistant S. mutans isolates.

Conclusion: It can be reasoned that the ethanolic extract of ant-nest plant gave potent and direct antibacterial effect on S. mutans.

Key words: Ant Nest; Antibacterial; Streptococcus mutans; Caries; Hyaluronic Acid


 
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Pubmed Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia. Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans. Natl J Physiol Pharm Pharmacol. 2018; 8(5): 745-749. doi:10.5455/njppp.2018.8.0102827012018


Web Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia. Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans. http://www.njppp.com/?mno=288841 [Access: October 01, 2021]. doi:10.5455/njppp.2018.8.0102827012018


AMA (American Medical Association) Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia. Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans. Natl J Physiol Pharm Pharmacol. 2018; 8(5): 745-749. doi:10.5455/njppp.2018.8.0102827012018



Vancouver/ICMJE Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia. Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans. Natl J Physiol Pharm Pharmacol. (2018), [cited October 01, 2021]; 8(5): 745-749. doi:10.5455/njppp.2018.8.0102827012018



Harvard Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia (2018) Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans. Natl J Physiol Pharm Pharmacol, 8 (5), 745-749. doi:10.5455/njppp.2018.8.0102827012018



Turabian Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia. 2018. Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans. National Journal of Physiology, Pharmacy and Pharmacology, 8 (5), 745-749. doi:10.5455/njppp.2018.8.0102827012018



Chicago Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia. "Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans." National Journal of Physiology, Pharmacy and Pharmacology 8 (2018), 745-749. doi:10.5455/njppp.2018.8.0102827012018



MLA (The Modern Language Association) Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia. "Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans." National Journal of Physiology, Pharmacy and Pharmacology 8.5 (2018), 745-749. Print. doi:10.5455/njppp.2018.8.0102827012018



APA (American Psychological Association) Style

Sri Agung Fitri Kusuma, Sulistiyaningsih Sulistiyaningsih, Devita Fauzia (2018) Anticaries activity of ethanolic extract from ant-nest plant (Myrmecodia Pendens Merr. & L.M Perry) against hyaluronic acid resistant Streptococcus mutans. National Journal of Physiology, Pharmacy and Pharmacology, 8 (5), 745-749. doi:10.5455/njppp.2018.8.0102827012018