Abstract
Background: Coronavirus disease was a challenge to the human beings, leading to a big stress. Many studies were done on people’s psychological well-being and solutions were made. However, the attention given to the students was inadequate. Hence, this study was done to find out the psychological effect on medical students before and after pandemic.

Aims and Objectives: The aims of this study were to assess the psychological impact of corona virus disease on M.B.B.S students by self-structured questionnaire.

Materials and Methods: This is a cross sectional study including 306 medical students from all the professional years, age 18–25 years, both males and females in a rural medical college of South India. Informed consent was obtained, those not willing for the study were excluded from the study. A self-structured questionnaire was given to the study participants and the answers were analyzed.

Results: Analysis was done by mean and standard deviation, frequency, and proportions. Out of 306 students, 65% were females and 35% were males. The sleeping cycle was affected for 40.2% of subjects. Appetite was abnormal for 20.59%, depression for 31.05%, and anxiety 33.66%. Anger increased in 24.51%. Many students had insufficient relaxation. About 57.84% participants expressed stress for online classes. For 77.78% students, academics were affected and 57.52% were frustrated.

Conclusion: In COVID-19 pandemic period, medical students expressed stress and anxiety in new study methods, sleep and appetite abnormality, increased anger, irritation, and frustration. Adequate measures to be taken for prevention of stress by relaxation techniques, yoga, etc.

Key words: COVID-19; Pandemic; Medical Students; Psychological; Questionnaire