E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala

Snigdha Parvathy Mohan, Santosh Ramakrishnan Pillai, Tomy Philip, Liya Roslin Joseph.

Abstract
Background: Hypertension is a major non-communicable disease and a large proportion of patients are not treated adequately even though several antihypertensive drugs and various guidelines are available.

Aims and Objectives: The aim of the study was to study the treatment pattern and effectiveness of the antihypertensive drugs by estimating the blood pressure (BP) control achieved based on Joint National Committee (JNC) 8 guidelines for the treatment of hypertension.

Materials and Methods: In this observational study, 92 patients with primary hypertension diagnosed since 1 1/2 years were included in the study. BP at the time of diagnosis and on subsequent follow-up visits and details of antihypertensive drugs prescribed during each visit were recorded, until target BP was achieved or till the end of the study period. Wilcoxon Signed Rank test and Mann–Whitney U test were used for analyzing the dependent and independent groups, respectively.

Results: Mean age of patients was 57.50 years and 54.3% of them were females. Majority received single drug (80.43%) compared to combination therapy (19.57%). Most frequently prescribed antihypertensive drug group was angiotensin receptor blockers (47.75%) followed by calcium channel blockers (41.44%) and most commonly prescribed individual drugs were losartan and amlodipine (both 25.22%). Seventy-three (79.30%) patients attained their target BP and the average time taken for the adequate control of BP was 5.67 (S.D ± 2.674) weeks.

Conclusion: JNC 8 guidelines were found to be effective in this study population.

Key words: Antihypertensive Drugs; Treatment Pattern; Effectiveness; Joint National Committee-8 Guidelines


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Snigdha Parvathy Mohan
Articles by Santosh Ramakrishnan Pillai
Articles by Tomy Philip
Articles by Liya Roslin Joseph
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Mohan SP, Pillai SR, Philip T, Joseph LR. Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala. Natl J Physiol Pharm Pharmacol. 2022; 12(12): 1995-1999. doi:10.5455/njppp.2022.12.03112202204042022


Web Style

Mohan SP, Pillai SR, Philip T, Joseph LR. Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala. https://www.njppp.com/?mno=99221 [Access: February 02, 2023]. doi:10.5455/njppp.2022.12.03112202204042022


AMA (American Medical Association) Style

Mohan SP, Pillai SR, Philip T, Joseph LR. Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala. Natl J Physiol Pharm Pharmacol. 2022; 12(12): 1995-1999. doi:10.5455/njppp.2022.12.03112202204042022



Vancouver/ICMJE Style

Mohan SP, Pillai SR, Philip T, Joseph LR. Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala. Natl J Physiol Pharm Pharmacol. (2022), [cited February 02, 2023]; 12(12): 1995-1999. doi:10.5455/njppp.2022.12.03112202204042022



Harvard Style

Mohan, S. P., Pillai, . S. R., Philip, . T. & Joseph, . L. R. (2022) Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala. Natl J Physiol Pharm Pharmacol, 12 (12), 1995-1999. doi:10.5455/njppp.2022.12.03112202204042022



Turabian Style

Mohan, Snigdha Parvathy, Santosh Ramakrishnan Pillai, Tomy Philip, and Liya Roslin Joseph. 2022. Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala. National Journal of Physiology, Pharmacy and Pharmacology, 12 (12), 1995-1999. doi:10.5455/njppp.2022.12.03112202204042022



Chicago Style

Mohan, Snigdha Parvathy, Santosh Ramakrishnan Pillai, Tomy Philip, and Liya Roslin Joseph. "Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 1995-1999. doi:10.5455/njppp.2022.12.03112202204042022



MLA (The Modern Language Association) Style

Mohan, Snigdha Parvathy, Santosh Ramakrishnan Pillai, Tomy Philip, and Liya Roslin Joseph. "Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala." National Journal of Physiology, Pharmacy and Pharmacology 12.12 (2022), 1995-1999. Print. doi:10.5455/njppp.2022.12.03112202204042022



APA (American Psychological Association) Style

Mohan, S. P., Pillai, . S. R., Philip, . T. & Joseph, . L. R. (2022) Impact of Eighth Joint National Committee guidelines on achievement of target blood pressure among hypertensive patients attending tertiary care hospital in South Kerala. National Journal of Physiology, Pharmacy and Pharmacology, 12 (12), 1995-1999. doi:10.5455/njppp.2022.12.03112202204042022