A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug

Kamal Kishore Khichi; Monika Sharma; Anusuya Gehlot; Rajkumar Rathore

doi:10.5455/njppp.2022.12.01020202225022022

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Online Publishing Date:
10 / 03 / 2022

Natl J Physiol Pharm Pharmacol. 2022; 12(4): 497-500

doi: 10.5455/njppp.2022.12.01020202225022022

A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug

Kamal Kishore Khichi, Monika Sharma, Anusuya Gehlot, Rajkumar Rathore.

Abstract
Background: Cuminum cyminum has been one of the commonly used home-based spices in India. It shows various properties such as antispasmodic, astringent, antiseptic, antioxidant, antimicrobial, analgesic, anti-inflammatory, antianxiety, anticonvulsant, and carminative.

Aim and Objective: This study aimed to evaluate the antianxiety property of C. cyminum and its comparison with diazepam on albino rats.

Materials and Methods: This study was conducted in Department of Pharmacology at a tertiary care center of Western Rajasthan. Adult albino rats of either sex (100–150 g) were divided into three groups. One group received distilled water and other two group received drugs – C. cyminum and Diazepam, respectively.

Results: Antianxiety effect of C. cyminum was not significant in lower and medium doses (300 and 750 mg/kg). Significant antianxiety effect of C. cyminum was seen in higher dose (1000 mg/kg).

Conclusion: On the basis of this study, it can be assumed that aqueous extract of C. cyminum could be a potential source to evaluate for the central nervous system disorders. Further studies are needed to explain the actual mechanism of action of C. cyminum at the cellular and molecular levels in detail.

Key words: Cuminum cyminum; Anti-anxiety; Diazepam

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Pubmed Style

Khichi KK, Sharma M, Gehlot A, Rathore R. A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug. Natl J Physiol Pharm Pharmacol. 2022; 12(4): 497-500. doi:10.5455/njppp.2022.12.01020202225022022

Web Style

Khichi KK, Sharma M, Gehlot A, Rathore R. A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug. https://www.njppp.com/?mno=141172 [Access: March 14, 2024]. doi:10.5455/njppp.2022.12.01020202225022022

AMA (American Medical Association) Style

Khichi KK, Sharma M, Gehlot A, Rathore R. A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug. Natl J Physiol Pharm Pharmacol. 2022; 12(4): 497-500. doi:10.5455/njppp.2022.12.01020202225022022

Vancouver/ICMJE Style

Khichi KK, Sharma M, Gehlot A, Rathore R. A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug. Natl J Physiol Pharm Pharmacol. (2022), [cited March 14, 2024]; 12(4): 497-500. doi:10.5455/njppp.2022.12.01020202225022022

Harvard Style

Khichi, K. K., Sharma, . M., Gehlot, . A. & Rathore, . R. (2022) A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug. Natl J Physiol Pharm Pharmacol, 12 (4), 497-500. doi:10.5455/njppp.2022.12.01020202225022022

Turabian Style

Khichi, Kamal Kishore, Monika Sharma, Anusuya Gehlot, and Rajkumar Rathore. 2022. A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug. National Journal of Physiology, Pharmacy and Pharmacology, 12 (4), 497-500. doi:10.5455/njppp.2022.12.01020202225022022

Chicago Style

Khichi, Kamal Kishore, Monika Sharma, Anusuya Gehlot, and Rajkumar Rathore. "A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 497-500. doi:10.5455/njppp.2022.12.01020202225022022

MLA (The Modern Language Association) Style

Khichi, Kamal Kishore, Monika Sharma, Anusuya Gehlot, and Rajkumar Rathore. "A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug." National Journal of Physiology, Pharmacy and Pharmacology 12.4 (2022), 497-500. Print. doi:10.5455/njppp.2022.12.01020202225022022

APA (American Psychological Association) Style

Khichi, K. K., Sharma, . M., Gehlot, . A. & Rathore, . R. (2022) A preliminary study of antianxiety effect of Cuminum cyminum and comparison with standard drug. National Journal of Physiology, Pharmacy and Pharmacology, 12 (4), 497-500. doi:10.5455/njppp.2022.12.01020202225022022

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