E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
27 / 05 / 2022

 


Perceived stress and cellular aging among medical students: A cross-sectional study

Chillu Sathish Chandra, Madhusudana Pulaganti, Athikari Chandra Sekhar, Bandi Hari Krishna.


Abstract
Background: There is little evidence in medical students on the connection between stress and telomere length (TL), which represents cellular aging.

Aim and Objective: We undertook this study to investigate the relationship between stress and cellular aging as measured by TL.

Materials and Methods: After obtaining permission from the Institute Ethics Committee, apparently healthy subjects between the ages of 18 and 25 years were recruited. Subjects were excluded if they are on any medication, subjects with a history of diabetes, hypertension, endocrine disorders, kidney disease, and hypertensive patients using drugs. The study tool was the Kessler10 (K10) psychological distress instrument. TL was determined using a previously described real-time quantitative polymerase chain reaction technique.

Results: The mean age of the participants was 19.23 ± 1.23 years. The data were divided based on K10 scores. Comparison was made between the K10 scores less than and more than 20. No significant difference in baseline characteristics was found except height. Further, there was no correlation between height with either TL or K10 scores. We found significantly lesser TL in individuals K10 score more than 20 (P < 0.00).

Conclusion: Given the high association between stress levels and TL shortening in medical students, this may contribute to premature aging as well as the process of development of several illnesses associated with short TL.

Key words: Medical Education; Stress; Telomere Length; Cellular Senescence


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Chillu Sathish Chandra
Articles by Madhusudana Pulaganti
Articles by Athikari Chandra Sekhar
Articles by Bandi Hari Krishna
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Chandra CS, Pulaganti M, Sekhar AC, Krishna BH. Perceived stress and cellular aging among medical students: A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2022; 12(7): 1003-1007. doi:10.5455/njppp.2022.12.05206202218052022


Web Style

Chandra CS, Pulaganti M, Sekhar AC, Krishna BH. Perceived stress and cellular aging among medical students: A cross-sectional study. https://www.njppp.com/?mno=17174 [Access: March 14, 2024]. doi:10.5455/njppp.2022.12.05206202218052022


AMA (American Medical Association) Style

Chandra CS, Pulaganti M, Sekhar AC, Krishna BH. Perceived stress and cellular aging among medical students: A cross-sectional study. Natl J Physiol Pharm Pharmacol. 2022; 12(7): 1003-1007. doi:10.5455/njppp.2022.12.05206202218052022



Vancouver/ICMJE Style

Chandra CS, Pulaganti M, Sekhar AC, Krishna BH. Perceived stress and cellular aging among medical students: A cross-sectional study. Natl J Physiol Pharm Pharmacol. (2022), [cited March 14, 2024]; 12(7): 1003-1007. doi:10.5455/njppp.2022.12.05206202218052022



Harvard Style

Chandra, C. S., Pulaganti, . M., Sekhar, . A. C. & Krishna, . B. H. (2022) Perceived stress and cellular aging among medical students: A cross-sectional study. Natl J Physiol Pharm Pharmacol, 12 (7), 1003-1007. doi:10.5455/njppp.2022.12.05206202218052022



Turabian Style

Chandra, Chillu Sathish, Madhusudana Pulaganti, Athikari Chandra Sekhar, and Bandi Hari Krishna. 2022. Perceived stress and cellular aging among medical students: A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 12 (7), 1003-1007. doi:10.5455/njppp.2022.12.05206202218052022



Chicago Style

Chandra, Chillu Sathish, Madhusudana Pulaganti, Athikari Chandra Sekhar, and Bandi Hari Krishna. "Perceived stress and cellular aging among medical students: A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 1003-1007. doi:10.5455/njppp.2022.12.05206202218052022



MLA (The Modern Language Association) Style

Chandra, Chillu Sathish, Madhusudana Pulaganti, Athikari Chandra Sekhar, and Bandi Hari Krishna. "Perceived stress and cellular aging among medical students: A cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 12.7 (2022), 1003-1007. Print. doi:10.5455/njppp.2022.12.05206202218052022



APA (American Psychological Association) Style

Chandra, C. S., Pulaganti, . M., Sekhar, . A. C. & Krishna, . B. H. (2022) Perceived stress and cellular aging among medical students: A cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 12 (7), 1003-1007. doi:10.5455/njppp.2022.12.05206202218052022