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Online Publishing Date:
25 / 05 / 2016

 


Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R.


Abstract
Background: Globally, diabetes mellitus has now emerged as a major public health problem, especially in India. Diabetic neuropathy may occur in nearly half of the patients with long-standing diabetes mellitus. In diabetes mellitus, the determinants of cardiac autonomic dysfunction were duration of diabetes, extent of glycemic control, age, and gender.

Aims and Objective: To study the various ECG abnormalities in type 2 diabetes mellitus patients when compared with control subjects.

Materials and Methods: The study was carried out as a hospital-based cross-sectional study among 50 diabetic patients and 50 age- and sex-matched control subjects. Resting ECG was recorded among study and control groups and compared. SPSS, version 20.0, was used for statistical analysis; unpaired t test was used to test the statistical difference in comparison of means, and a p value of <0.05 was considered statistically significant.

Result: The study results showed that certain ECG changes such as resting heart rate, RR interval, PR interval, QRS axis, and QTc interval significantly varied between study and control groups. Abnormal heart rate response to deep breathing and postural hypotension were observed at higher frequency among patients with diabetes mellitus.

Conclusion: Evaluation of various cardiovascular reflexes and ECG in type 2 diabetic patients may serve as a feasible technique to determine the presence of cardiac dysautonomia.

Key words: Diabetes Mellitus; Cardiac Autonomic Dysfunction; ECG Changes


 
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Pubmed Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R. Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study. Natl J Physiol Pharm Pharmacol. 2016; 6(3): 178-181. doi:10.5455/njppp.2016.6.27122015107

Web Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R. Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study. https://www.njppp.com/?mno=211974 [Access: March 14, 2024]. doi:10.5455/njppp.2016.6.27122015107

AMA (American Medical Association) Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R. Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study. Natl J Physiol Pharm Pharmacol. 2016; 6(3): 178-181. doi:10.5455/njppp.2016.6.27122015107


Vancouver/ICMJE Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R. Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study. Natl J Physiol Pharm Pharmacol. (2016), [cited March 14, 2024]; 6(3): 178-181. doi:10.5455/njppp.2016.6.27122015107


Harvard Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R (2016) Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study. Natl J Physiol Pharm Pharmacol, 6 (3), 178-181. doi:10.5455/njppp.2016.6.27122015107


Turabian Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R. 2016. Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 6 (3), 178-181. doi:10.5455/njppp.2016.6.27122015107


Chicago Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R. "Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 178-181. doi:10.5455/njppp.2016.6.27122015107


MLA (The Modern Language Association) Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R. "Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study." National Journal of Physiology, Pharmacy and Pharmacology 6.3 (2016), 178-181. Print. doi:10.5455/njppp.2016.6.27122015107


APA (American Psychological Association) Style

Vijay Prasad C, Darshan Savery M, Vishnu Prasad R (2016) Cardiac autonomic dysfunction and ECG abnormalities in patients with type 2 diabetes mellitus—a comparative cross-sectional study. National Journal of Physiology, Pharmacy and Pharmacology, 6 (3), 178-181. doi:10.5455/njppp.2016.6.27122015107


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