E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
11 / 01 / 2017

 


Evaluation of vascular function in depigmented black women: Comparative study

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb.


Abstract
Background: Prolonged application of skin depigmenting substances could expose human organism to serious general complications such as hypertension or diabetes. Artificial depigmentation (AD) is a widespread practice within Sub-Saharan Africa subjects. AD is based on the use of dermocorticoides which could lead to vascular complications.

Aims and Objectives: Our aim was to evaluate the vascular function in depigmented Senegalese women.

Materials and Methods: Thirty six depigmented (depigmented group) and 36 undepigmented black women (control group) participated in the study. They were aged 33.10 ± 7 years and 30.22 ± 6 years, respectively. Brachial artery flow mediated dilation (FMD) was measured in two groups. Biochemical and cardiovascular profiles of our study population were evaluated. The duration of depigmenting products exposure was evaluated in depigmented subjects.

Results: Our study showed an abnormal kinetic of FMD in depigmented group compared to control group. Mean arterial pressure was 95.9 ± 8.8 mmHg in depigmented subjects and 89.6 ± 6.2 mmHg for control subjects and a significant difference was observed (P = 0.002) while triglycerides was significantly different (P = 0.01) between the two groups (0.8 ± 0.3 and 0.6 ± 0.2 g/L, respectively). FMD was significantly and positively correlated with exposure time (r = 0.25; P = 0.029).

Conclusion: Prolonged percutaneous application of depigmentation products could alter metabolic and vascular functions, and consequently install cardiovascular risks. Thus, we recommended ways to prevent of AD in the African population.

Key words: Artificial Depigmentation; Black Population; Vascular Function


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Arame Mbengue
Articles by Mor Diaw
Articles by Gerard Akpo
Articles by Hamidou Deme
Articles by Valentin Ouedraogo
Articles by Abdou K Sow
Articles by Oumar Diop
Articles by Arnaud Jean Florent Tiendrebeogo
Articles by Fatoumata Ba
Articles by Mamadou Mbdji
Articles by Aissatou Seck
Articles by Saliamata Diagne Houndjo
Articles by Maimouna Toure
Articles by Mame Saloum Coly
Articles by Fatou Bintou Sarr
Articles by Abdoulaye Ba
Articles by Abdoulaye Samb
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb. Evaluation of vascular function in depigmented black women: Comparative study. Natl J Physiol Pharm Pharmacol. 2017; 7(4): 420-424. doi:10.5455/njppp.2017.7.1233202012017


Web Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb. Evaluation of vascular function in depigmented black women: Comparative study. https://www.njppp.com/?mno=251168 [Access: March 15, 2024]. doi:10.5455/njppp.2017.7.1233202012017


AMA (American Medical Association) Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb. Evaluation of vascular function in depigmented black women: Comparative study. Natl J Physiol Pharm Pharmacol. 2017; 7(4): 420-424. doi:10.5455/njppp.2017.7.1233202012017



Vancouver/ICMJE Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb. Evaluation of vascular function in depigmented black women: Comparative study. Natl J Physiol Pharm Pharmacol. (2017), [cited March 15, 2024]; 7(4): 420-424. doi:10.5455/njppp.2017.7.1233202012017



Harvard Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb (2017) Evaluation of vascular function in depigmented black women: Comparative study. Natl J Physiol Pharm Pharmacol, 7 (4), 420-424. doi:10.5455/njppp.2017.7.1233202012017



Turabian Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb. 2017. Evaluation of vascular function in depigmented black women: Comparative study. National Journal of Physiology, Pharmacy and Pharmacology, 7 (4), 420-424. doi:10.5455/njppp.2017.7.1233202012017



Chicago Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb. "Evaluation of vascular function in depigmented black women: Comparative study." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 420-424. doi:10.5455/njppp.2017.7.1233202012017



MLA (The Modern Language Association) Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb. "Evaluation of vascular function in depigmented black women: Comparative study." National Journal of Physiology, Pharmacy and Pharmacology 7.4 (2017), 420-424. Print. doi:10.5455/njppp.2017.7.1233202012017



APA (American Psychological Association) Style

Arame Mbengue, Mor Diaw, Gerard Akpo, Hamidou Deme, Valentin Ouedraogo, Abdou K Sow, Oumar Diop, Arnaud Jean Florent Tiendrebeogo, Fatoumata Ba, Mamadou Mbdji, Aissatou Seck, Saliamata Diagne Houndjo, Maimouna Toure, Mame Saloum Coly, Fatou Bintou Sarr, Abdoulaye Ba, Abdoulaye Samb (2017) Evaluation of vascular function in depigmented black women: Comparative study. National Journal of Physiology, Pharmacy and Pharmacology, 7 (4), 420-424. doi:10.5455/njppp.2017.7.1233202012017