Clonazepam-induced acute liver injury: A case report

Malini Muraleedharan Nair; Dhanya Susan Abraham; Neethu C M

doi:10.5455/njppp.2017.7.0723308072017

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Case Report
Online Published: 11 Oct 2017

Natl J Physiol Pharm Pharmacol. 2017; 7(12): 1439-1440

doi: 10.5455/njppp.2017.7.0723308072017

Clonazepam-induced acute liver injury: A case report

Malini Muraleedharan Nair, Dhanya Susan Abraham, Neethu C M.

Cited By:2

Abstract
Clonazepam belongs to the benzodiazepine class of drugs (benzodiazepine derivative). It is used both as an anticonvulsant and in the treatment of panic disorder with or without agoraphobia. The most frequent adverse drug reactions of clonazepam are sedation or drowsiness, ataxia or hypotonia, and behavioral disturbances. Hepatomegaly and transient elevations in serum aminotransferases and alkaline phosphatase concentrations may occur in patients receiving this drug, but the frequency of the reaction has not been well defined. Here, we report that an acute psychosis case was the patients laboratory reports showed a transient elevation in serum transaminases and alkaline phosphatase levels after clonazepam was administered.

Key words: Clonazepam; Benzodiazepines; Serum Transaminases; Alkaline Phosphatase; Adverse Drug Reaction

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Pubmed Style

Nair MM, Abraham DS, M NC. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. 2017; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Web Style

Nair MM, Abraham DS, M NC. Clonazepam-induced acute liver injury: A case report. https://www.njppp.com/?mno=271177 [Access: June 27, 2026]. doi:10.5455/njppp.2017.7.0723308072017

AMA (American Medical Association) Style

Nair MM, Abraham DS, M NC. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. 2017; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Vancouver/ICMJE Style

Nair MM, Abraham DS, M NC. Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol. (2017), [cited June 27, 2026]; 7(12): 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Harvard Style

Nair, M. M., Abraham, . D. S. & M, . N. C. (2017) Clonazepam-induced acute liver injury: A case report. Natl J Physiol Pharm Pharmacol, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Turabian Style

Nair, Malini Muraleedharan, Dhanya Susan Abraham, and Neethu C M. 2017. Clonazepam-induced acute liver injury: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

Chicago Style

Nair, Malini Muraleedharan, Dhanya Susan Abraham, and Neethu C M. "Clonazepam-induced acute liver injury: A case report." National Journal of Physiology, Pharmacy and Pharmacology 7 (2017), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

MLA (The Modern Language Association) Style

Nair, Malini Muraleedharan, Dhanya Susan Abraham, and Neethu C M. "Clonazepam-induced acute liver injury: A case report." National Journal of Physiology, Pharmacy and Pharmacology 7.12 (2017), 1439-1440. Print. doi:10.5455/njppp.2017.7.0723308072017

APA (American Psychological Association) Style

Nair, M. M., Abraham, . D. S. & M, . N. C. (2017) Clonazepam-induced acute liver injury: A case report. National Journal of Physiology, Pharmacy and Pharmacology, 7 (12), 1439-1440. doi:10.5455/njppp.2017.7.0723308072017

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