Central analgesic activity of ethanolic extract of Moringa oleifera seeds

Abdul Haseeb; Mohammed Ziauddin Sarkhil; Mohammed Fayazuddin; Farida Ahmad

doi:10.5455/njppp.2019.9.0519223052019

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Online Published: 03 Jun 2019

Natl J Physiol Pharm Pharmacol. 2019; 9(8): 767-770

doi: 10.5455/njppp.2019.9.0519223052019

Central analgesic activity of ethanolic extract of Moringa oleifera seeds

Abdul Haseeb, Mohammed Ziauddin Sarkhil, Mohammed Fayazuddin, Farida Ahmad.

Cited By:2

Abstract
Background: Moringa oleifera Lam. commonly known as the drumstick tree is an exceptionally nutritious vegetable tree with a variety of potential medicinal uses.

Aims and Objectives: The objective of this study was to evaluate the central analgesic activity of ethanolic extract of M. oleifera (EEMO) seeds.

Materials and Methods: The central analgesic activity was studied using Eddys hot plate method and tail immersion method in Albino Wistar rats of either sex weighing 150200 g at doses of EEMO 50 mg/kg, 100 mg/kg, and 200 mg/kg. Statistical significance was calculated using one-way analysis of variance followed by post hoc Dunnetts test.

Results: EEMO at all three doses 50 mg/kg, 100 mg/kg, and 200 mg/kg exhibited central analgesic activity by significantly increasing the reaction time in Eddys hot plate method and tail immersion method when compared to control group.

Conclusion: EEMO seeds exhibit central analgesic activity in experimental animals.

Key words: Moringa oleifera; Eddys Hot Plate Method; Tail Immersion Method; Central Analgesic Activity

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Pubmed Style

Haseeb A, Sarkhil MZ, Fayazuddin M, Ahmad F. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. Natl J Physiol Pharm Pharmacol. 2019; 9(8): 767-770.

doi:10.5455/njppp.2019.9.0519223052019

Web Style

Haseeb A, Sarkhil MZ, Fayazuddin M, Ahmad F. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. https://www.njppp.com/?mno=50053 [Access: June 27, 2026].

doi:10.5455/njppp.2019.9.0519223052019

AMA (American Medical Association) Style

Haseeb A, Sarkhil MZ, Fayazuddin M, Ahmad F. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. Natl J Physiol Pharm Pharmacol. 2019; 9(8): 767-770.

doi:10.5455/njppp.2019.9.0519223052019

Vancouver/ICMJE Style

Haseeb A, Sarkhil MZ, Fayazuddin M, Ahmad F. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. Natl J Physiol Pharm Pharmacol. (2019), [cited June 27, 2026]; 9(8): 767-770.

doi:10.5455/njppp.2019.9.0519223052019

Harvard Style

Haseeb, A., Sarkhil, . M. Z., Fayazuddin, . M. & Ahmad, . F. (2019) Central analgesic activity of ethanolic extract of Moringa oleifera seeds. Natl J Physiol Pharm Pharmacol, 9 (8), 767-770.

doi:10.5455/njppp.2019.9.0519223052019

Turabian Style

Haseeb, Abdul, Mohammed Ziauddin Sarkhil, Mohammed Fayazuddin, and Farida Ahmad. 2019. Central analgesic activity of ethanolic extract of Moringa oleifera seeds. National Journal of Physiology, Pharmacy and Pharmacology, 9 (8), 767-770.

doi:10.5455/njppp.2019.9.0519223052019

Chicago Style

Haseeb, Abdul, Mohammed Ziauddin Sarkhil, Mohammed Fayazuddin, and Farida Ahmad. "Central analgesic activity of ethanolic extract of Moringa oleifera seeds." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 767-770.

doi:10.5455/njppp.2019.9.0519223052019

MLA (The Modern Language Association) Style

doi:10.5455/njppp.2019.9.0519223052019

APA (American Psychological Association) Style

Haseeb, A., Sarkhil, . M. Z., Fayazuddin, . M. & Ahmad, . F. (2019) Central analgesic activity of ethanolic extract of Moringa oleifera seeds. National Journal of Physiology, Pharmacy and Pharmacology, 9 (8), 767-770.

doi:10.5455/njppp.2019.9.0519223052019

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