Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra

Balasaheb Baburao Vikhe; Muktpal Marotrao Bhalerao

doi:10.5455/njppp.2019.9.0727409092019

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Original Research
Online Published: 14 Sep 2019

Natl J Physiol Pharm Pharmacol. 2019; 9(11): 1130-1133

doi: 10.5455/njppp.2019.9.0727409092019

Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra

Balasaheb Baburao Vikhe, Muktpal Marotrao Bhalerao.

Abstract
Background: Pregnancy is a phenomenon of maternal adaptation to the increasing demands of the growing fetus. Pregnancy causes many visible and invisible changes in human body and it represents one of the best examples of selective adaptation in respiratory physiology. Many previous studies observed significant changes in pulmonary function tests in pregnant women as compare to non-pregnant women.

Aims and Objectives: This study aims to study and compare pulmonary function tests, especially forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) in healthy pregnant women and healthy non-pregnant women.

Materials and Methods: This casecontrol study was carried in the Department of Physiology, Rural Medical College, Loni, in collaboration with Pravara Rural Hospital, Loni, in Maharashtra. The study was carried out after the approval of the institutional ethics committee registration No. PMT/PIMS/RC/2012/25. Four hundred subjects were selected and divided into four groups, non-pregnant women, and normal pregnant women of the 1st, 2nd, and 3rd trimesters. Pulmonary function tests were done using Spirovit SP-1.

Results: Highly significant decrease in the FEV1 and FVC (P < 0.001) was seen in the 1st, 2nd, and 3rd trimesters of healthy pregnant women as compared to healthy non-pregnant women.

Conclusion: FEV1 and FVC were significantly decreased in all the three trimesters of pregnancy. The mechanical effect of growing uterus and the interplay of estrogen and progesterone are attributed to the changes observed in pulmonary function test among pregnant women.

Key words: Forced Expiratory Volume in 1 s; Forced Vital Capacity; Pregnancy

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Pubmed Style

Vikhe BB, Bhalerao MM. Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra. Natl J Physiol Pharm Pharmacol. 2019; 9(11): 1130-1133.

doi:10.5455/njppp.2019.9.0727409092019

Web Style

Vikhe BB, Bhalerao MM. Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra. https://www.njppp.com/?mno=58486 [Access: June 27, 2026].

doi:10.5455/njppp.2019.9.0727409092019

AMA (American Medical Association) Style

Vikhe BB, Bhalerao MM. Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra. Natl J Physiol Pharm Pharmacol. 2019; 9(11): 1130-1133.

doi:10.5455/njppp.2019.9.0727409092019

Vancouver/ICMJE Style

Vikhe BB, Bhalerao MM. Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra. Natl J Physiol Pharm Pharmacol. (2019), [cited June 27, 2026]; 9(11): 1130-1133.

doi:10.5455/njppp.2019.9.0727409092019

Harvard Style

Vikhe, B. B. & Bhalerao, . M. M. (2019) Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra. Natl J Physiol Pharm Pharmacol, 9 (11), 1130-1133.

doi:10.5455/njppp.2019.9.0727409092019

Turabian Style

Vikhe, Balasaheb Baburao, and Muktpal Marotrao Bhalerao. 2019. Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra. National Journal of Physiology, Pharmacy and Pharmacology, 9 (11), 1130-1133.

doi:10.5455/njppp.2019.9.0727409092019

Chicago Style

Vikhe, Balasaheb Baburao, and Muktpal Marotrao Bhalerao. "Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra." National Journal of Physiology, Pharmacy and Pharmacology 9 (2019), 1130-1133.

doi:10.5455/njppp.2019.9.0727409092019

MLA (The Modern Language Association) Style

doi:10.5455/njppp.2019.9.0727409092019

APA (American Psychological Association) Style

Vikhe, B. B. & Bhalerao, . M. M. (2019) Study of forced expiratory volume in one second and forced vital capacity in normal pregnancy from Western Maharashtra. National Journal of Physiology, Pharmacy and Pharmacology, 9 (11), 1130-1133.

doi:10.5455/njppp.2019.9.0727409092019

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