E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
16 / 07 / 2022

 


Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery

Deepti Swain, Asitkumar Sethi, Prasantkumar Bal, Kamalakanta Swain, Sidharth Sraban Routray.


Abstract
Background: Paravertebral block can be given for pain management after modified radical mastectomy (MRM). Although many additives to ropivacaine in PVB have been tried for post-operative analgesia, none has been found ideal.

Aims and Objectives: We have compared the duration of analgesia in PVB using adjuvant like dexmedetomidine with ropivacaine after MRM.

Materials and Methods: Sixty female patients posted for MRM and axillary dissection were split into two groups. Group R administered ultrasound-guided PVB with 20 ml ropivacaine 0.5% and Group RD administered 20 ml of 0.5% ropivacaine with dexmedetomidine 1 mcg/kg. After confirming PVB, surgery was done under general anesthesia in all patients. Time for 1st analgesia requirement was the main objective of our trial. Other objectives were to record visual analog scale scores and total analgesic need.

Results: Post-operative analgesia duration was increased in the group RD (7.11 ± 1.42 h) in contrary to Group R (3.68 ± 1.85 h). Total paracetamol consumption post-operative 24 h was decreased in Group RD (1.63 ±0.89 g) in contrary to Group R (2.74 ± 0.76 g).

Conclusion: Dexmedetomidine in PVB provides prolonged pain relief after MRM.

Key words: Dexmedetomidine; Ropivacaine; PVB; Analgesia


 
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How to Cite this Article
Pubmed Style

Swain D, Sethi A, Bal P, Swain K, Routray SS. Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery. Natl J Physiol Pharm Pharmacol. 2023; 13(2): 340-343. doi:10.5455/njppp.2023.13.07331202207072022


Web Style

Swain D, Sethi A, Bal P, Swain K, Routray SS. Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery. https://www.njppp.com/?mno=76189 [Access: March 15, 2024]. doi:10.5455/njppp.2023.13.07331202207072022


AMA (American Medical Association) Style

Swain D, Sethi A, Bal P, Swain K, Routray SS. Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery. Natl J Physiol Pharm Pharmacol. 2023; 13(2): 340-343. doi:10.5455/njppp.2023.13.07331202207072022



Vancouver/ICMJE Style

Swain D, Sethi A, Bal P, Swain K, Routray SS. Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery. Natl J Physiol Pharm Pharmacol. (2023), [cited March 15, 2024]; 13(2): 340-343. doi:10.5455/njppp.2023.13.07331202207072022



Harvard Style

Swain, D., Sethi, . A., Bal, . P., Swain, . K. & Routray, . S. S. (2023) Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery. Natl J Physiol Pharm Pharmacol, 13 (2), 340-343. doi:10.5455/njppp.2023.13.07331202207072022



Turabian Style

Swain, Deepti, Asitkumar Sethi, Prasantkumar Bal, Kamalakanta Swain, and Sidharth Sraban Routray. 2023. Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery. National Journal of Physiology, Pharmacy and Pharmacology, 13 (2), 340-343. doi:10.5455/njppp.2023.13.07331202207072022



Chicago Style

Swain, Deepti, Asitkumar Sethi, Prasantkumar Bal, Kamalakanta Swain, and Sidharth Sraban Routray. "Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 340-343. doi:10.5455/njppp.2023.13.07331202207072022



MLA (The Modern Language Association) Style

Swain, Deepti, Asitkumar Sethi, Prasantkumar Bal, Kamalakanta Swain, and Sidharth Sraban Routray. "Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery." National Journal of Physiology, Pharmacy and Pharmacology 13.2 (2023), 340-343. Print. doi:10.5455/njppp.2023.13.07331202207072022



APA (American Psychological Association) Style

Swain, D., Sethi, . A., Bal, . P., Swain, . K. & Routray, . S. S. (2023) Efficacy of dexmedetomidine as adjuvant to ropivacaine in paravertebral block for post-operative analgesia in breast cancer surgery. National Journal of Physiology, Pharmacy and Pharmacology, 13 (2), 340-343. doi:10.5455/njppp.2023.13.07331202207072022