E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research 


Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study

Kiran Bhave, Aashiana Thiyam, Tejal Patel, Monisha Chavan, Shashank Desai.

Abstract
Background: COVID-19 caused immense morbidity and mortality worldwide and was declared a pandemic on March 11, 2020, by the World Health Organization. Lack of effective treatments directed researchers to various interventional strategies, such as development of new drugs or vaccines, drug repurposing models, and AYUSH formulations, for prophylaxis and treatment of COVID-19.

Aim and Objectives: The information obtained from registered COVID-19 trials for the year 2020, will help to identify the various aspects for therapeutics and types of study designs used for achieving different objectives, so as to guide researchers for similar future projects.

Materials and Methods: A descriptive, observational study was conducted on COVID-19-related clinical trials registered in Clinical Trials Registry of India during calendar year 2020. The details were noted in a predesigned pro forma and evaluated.

Results: Of the 946 registered trials, majority were single center (82.76%), interventional (50.7%), randomized (73.1%), open-labeled (61.9%), and prospective in nature (96%). Our study revealed that 40.16% trials used modern medicine while 26.53% used AYUSH formulations. The psychological impact of COVID-19 pandemic was studied in 121 trials, of which 118 trials showed negative impact on the mental well-being.

Conclusion: Our study provides thorough insight about the on-going research in our country, especially about various drug repurposing strategies and government supported AYUSH interventions. This may act as a foundation for future investigators to identify any lacunae in the current studies, helping them to diversify their objectives accordingly, so as to encourage quality research in our country.

Key words: COVID-19; Coronavirus; COVID Trials; AYUSH


 
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How to Cite this Article
Pubmed Style

Bhave K, Thiyam A, Patel T, Chavan M, Desai S. Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study. Natl J Physiol Pharm Pharmacol. 2022; 12(10): 1669-1674. doi:10.5455/njppp.2022.12.08408202206092022


Web Style

Bhave K, Thiyam A, Patel T, Chavan M, Desai S. Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study. https://www.njppp.com/?mno=107927 [Access: December 01, 2022]. doi:10.5455/njppp.2022.12.08408202206092022


AMA (American Medical Association) Style

Bhave K, Thiyam A, Patel T, Chavan M, Desai S. Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study. Natl J Physiol Pharm Pharmacol. 2022; 12(10): 1669-1674. doi:10.5455/njppp.2022.12.08408202206092022



Vancouver/ICMJE Style

Bhave K, Thiyam A, Patel T, Chavan M, Desai S. Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study. Natl J Physiol Pharm Pharmacol. (2022), [cited December 01, 2022]; 12(10): 1669-1674. doi:10.5455/njppp.2022.12.08408202206092022



Harvard Style

Bhave, K., Thiyam, . A., Patel, . T., Chavan, . M. & Desai, . S. (2022) Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study. Natl J Physiol Pharm Pharmacol, 12 (10), 1669-1674. doi:10.5455/njppp.2022.12.08408202206092022



Turabian Style

Bhave, Kiran, Aashiana Thiyam, Tejal Patel, Monisha Chavan, and Shashank Desai. 2022. Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study. National Journal of Physiology, Pharmacy and Pharmacology, 12 (10), 1669-1674. doi:10.5455/njppp.2022.12.08408202206092022



Chicago Style

Bhave, Kiran, Aashiana Thiyam, Tejal Patel, Monisha Chavan, and Shashank Desai. "Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study." National Journal of Physiology, Pharmacy and Pharmacology 12 (2022), 1669-1674. doi:10.5455/njppp.2022.12.08408202206092022



MLA (The Modern Language Association) Style

Bhave, Kiran, Aashiana Thiyam, Tejal Patel, Monisha Chavan, and Shashank Desai. "Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study." National Journal of Physiology, Pharmacy and Pharmacology 12.10 (2022), 1669-1674. Print. doi:10.5455/njppp.2022.12.08408202206092022



APA (American Psychological Association) Style

Bhave, K., Thiyam, . A., Patel, . T., Chavan, . M. & Desai, . S. (2022) Analysis of COVID-19-related clinical trials registered in the Clinical Trial Registry of India in 2020: A descriptive study. National Journal of Physiology, Pharmacy and Pharmacology, 12 (10), 1669-1674. doi:10.5455/njppp.2022.12.08408202206092022