Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center

Sanjeev Kumar; Chandani Surani; Meghana Chauhan

doi:10.5455/njppp.2023.13.09447202201102022

2023, Vol: 13, Issue: 5

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Natl J Physiol Pharm Pharmacol. 2023; 13(5): 967-970

doi: 10.5455/njppp.2023.13.09447202201102022

Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center

Sanjeev Kumar, Chandani Surani, Meghana Chauhan.

Abstract
Background: Emergence of extended spectrum β-lactamase (ESBL) producing strains of Gram-negative bacteria can lead to serious infections frequently complicates the clinical and treatment outcome.

Aims and Objectives: The purpose of this study was to know the prevalence of ESBLs and to know the most common Gram-negative bacteria, which produce ESBLs at our health-care facility.

Materials and Methods: This study comprised all of the isolates of Gram-negative bacteria that were acquired from various clinical samples. For the purpose of the investigation, a sample of an isolate that showed resistance to two or more third-generation cephalosporins was taken. ESBL detection and antibiotic sensitivity tests were carried out using conventional microbiological techniques.

Results: We isolated a total of 284 Gram-negative bacteria and 54 (19%) were identified as ESBL producers. Out 54 ESBL producers, 18 (33%) isolates were Escherichia coli, 11 (20%) were Pseudomonas aeruginosa, 12 (22%) were Klebsiellae, 6 (11%) were Enterobacter, 2 (4%) were Citrobacter, 4 (8%) were Acinetobacter, and 1 (2%) were Serratia spp.

Conclusion: Clinical decision-makers can make the best antibiotic treatment by regularly monitoring multi-drug resistant bacteria like ESBL producers. This also helps to improve infection control procedures. In addition, we must maintain reserve medications like carbapenems on hand for judicial use.

Key words: Extended Spectrum Β-Lactamase; Screening Test; Prevalence; Regular Monitoring

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Pubmed Style

Kumar S, Surani C, Chauhan M. Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center. Natl J Physiol Pharm Pharmacol. 2023; 13(5): 967-970. doi:10.5455/njppp.2023.13.09447202201102022

Web Style

Kumar S, Surani C, Chauhan M. Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center. https://www.njppp.com/?mno=115374 [Access: May 01, 2023]. doi:10.5455/njppp.2023.13.09447202201102022

AMA (American Medical Association) Style

Kumar S, Surani C, Chauhan M. Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center. Natl J Physiol Pharm Pharmacol. 2023; 13(5): 967-970. doi:10.5455/njppp.2023.13.09447202201102022

Vancouver/ICMJE Style

Kumar S, Surani C, Chauhan M. Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center. Natl J Physiol Pharm Pharmacol. (2023), [cited May 01, 2023]; 13(5): 967-970. doi:10.5455/njppp.2023.13.09447202201102022

Harvard Style

Kumar, S., Surani, . C. & Chauhan, . M. (2023) Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center. Natl J Physiol Pharm Pharmacol, 13 (5), 967-970. doi:10.5455/njppp.2023.13.09447202201102022

Turabian Style

Kumar, Sanjeev, Chandani Surani, and Meghana Chauhan. 2023. Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center. National Journal of Physiology, Pharmacy and Pharmacology, 13 (5), 967-970. doi:10.5455/njppp.2023.13.09447202201102022

Chicago Style

Kumar, Sanjeev, Chandani Surani, and Meghana Chauhan. "Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center." National Journal of Physiology, Pharmacy and Pharmacology 13 (2023), 967-970. doi:10.5455/njppp.2023.13.09447202201102022

MLA (The Modern Language Association) Style

Kumar, Sanjeev, Chandani Surani, and Meghana Chauhan. "Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center." National Journal of Physiology, Pharmacy and Pharmacology 13.5 (2023), 967-970. Print. doi:10.5455/njppp.2023.13.09447202201102022

APA (American Psychological Association) Style

Kumar, S., Surani, . C. & Chauhan, . M. (2023) Detection and prevalence of extended spectrum β-lactamases in gram-negative bacteria at our health-care center. National Journal of Physiology, Pharmacy and Pharmacology, 13 (5), 967-970. doi:10.5455/njppp.2023.13.09447202201102022

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