Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension

Shailaja Patil; Anita Herur; S V Brid; Surekharani Chinagudi; G V Shashikala; Roopa Ankad

doi:10.5455/njppp.2015.5.130620142

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Original Research
Online Published: 18 Jan 2015

Natl J Physiol Pharm Pharmacol. 2015; 5(1): 65-67

doi: 10.5455/njppp.2015.5.130620142

Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension

Shailaja Patil, Anita Herur, S V Brid, Surekharani Chinagudi, G V Shashikala, Roopa Ankad.

Abstract
Background: Several risk factors such as systemic hypertension, obesity, and body mass index (BMI) have been associated with increased intraocular pressure (IOP). This raised IOP can lead to irreversible optic nerve damage, causing blindness.

Aims & Objective: To evaluate the effects of blood pressure (BP) and BMI on IOP and thereby analyze the predisposition to glaucoma in children of patients with hypertension.

Materials and Methods: This observational study was conducted on medical undergraduates. Students with family history of hypertension were taken as cases, and equal number of students with no family history of hypertension were taken as controls.

Weight, height, BP, and IOP were recorded and compared in both the groups. Statistical analysis was done by Student t-test and Pearson correlation.

Results: Cases exhibited lower values for IOP, mean arterial pressure (MAP), and diastolic blood pressure. In cases, a positive correlation was found between both IOP and MAP and IOP and BMI, whereas in controls it was found only between IOP and BMI.

Conclusion: The results indicate that BP is an important determinant factor in regulation of IOP in children of patients with hypertension rather than those of individuals with normotension. Hence, children of patients with hypertension have to keep a check on their BPs as well as IOP to prevent the complications of early-onset ocular hypertension and thereby, glaucoma.
INTRODUCTION

Key words: Glaucoma; intraocular pressure; hypertension; offsprings of hypertensives

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Pubmed Style

Patil S, Herur A, Brid SV, Chinagudi S, Shashikala GV, Ankad R. Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension. Natl J Physiol Pharm Pharmacol. 2015; 5(1): 65-67. doi:10.5455/njppp.2015.5.130620142

Web Style

Patil S, Herur A, Brid SV, Chinagudi S, Shashikala GV, Ankad R. Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension. https://www.njppp.com/?mno=161202 [Access: July 09, 2025]. doi:10.5455/njppp.2015.5.130620142

AMA (American Medical Association) Style

Patil S, Herur A, Brid SV, Chinagudi S, Shashikala GV, Ankad R. Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension. Natl J Physiol Pharm Pharmacol. 2015; 5(1): 65-67. doi:10.5455/njppp.2015.5.130620142

Vancouver/ICMJE Style

Patil S, Herur A, Brid SV, Chinagudi S, Shashikala GV, Ankad R. Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension. Natl J Physiol Pharm Pharmacol. (2015), [cited July 09, 2025]; 5(1): 65-67. doi:10.5455/njppp.2015.5.130620142

Harvard Style

Patil, S., Herur, . A., Brid, . S. V., Chinagudi, . S., Shashikala, . G. V. & Ankad, . R. (2015) Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension. Natl J Physiol Pharm Pharmacol, 5 (1), 65-67. doi:10.5455/njppp.2015.5.130620142

Turabian Style

Patil, Shailaja, Anita Herur, S V Brid, Surekharani Chinagudi, G V Shashikala, and Roopa Ankad. 2015. Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension. National Journal of Physiology, Pharmacy and Pharmacology, 5 (1), 65-67. doi:10.5455/njppp.2015.5.130620142

Chicago Style

Patil, Shailaja, Anita Herur, S V Brid, Surekharani Chinagudi, G V Shashikala, and Roopa Ankad. "Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension." National Journal of Physiology, Pharmacy and Pharmacology 5 (2015), 65-67. doi:10.5455/njppp.2015.5.130620142

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Patil, S., Herur, . A., Brid, . S. V., Chinagudi, . S., Shashikala, . G. V. & Ankad, . R. (2015) Analysis of predisposition to primary open-angle glaucoma in children of patients with hypertension. National Journal of Physiology, Pharmacy and Pharmacology, 5 (1), 65-67. doi:10.5455/njppp.2015.5.130620142

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