Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.

Ateendra Singh; Anamika Singh; Omi Chouhan; Gyan Prakash Tandi; Mitali Dua; Anusuya Gehlot

doi:10.5455/njppp.2016.6.09122015123

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Online Published: 05 Jul 2016

Natl J Physiol Pharm Pharmacol. 2016; 6(4): 286-290

doi: 10.5455/njppp.2016.6.09122015123

Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.

Ateendra Singh, Anamika Singh, Omi Chouhan, Gyan Prakash Tandi, Mitali Dua, Anusuya Gehlot.

Cited By:19

Abstract
Background: Murraya koenigii, commonly known as karipatta or curry leaf, is analgesic and can be used effectively against inflammation and itching. The various pharmacological activities such as vasodilation, antimicrobial, antidiabetic, antiulcer, analgesic, phagocytic, and antioxidant activities of this plant have also been reported.

Aims and Objectives: To evaluate the anti-inflammatory and analgesic activity of aqueous extract of dried leaves of M. koenigii Linn. in male Wistar rats.

Materials and Methods: Adult male Wistar rats (100150 g body weight) were used in this study. Aqueous extract of M. koenigii Linn. was used to evaluate acute anti-inflammatory and analgesic activity by plethysmometer and hot plate method by oral administration at doses of 100, 300, and 500 mg/kg body weight in healthy albino rats.

Result: In acute studies, the aqueous extract showed anti-inflammatory activity by significant reduction in the paw edema volume, in a dose-dependent manner when compared with the control and standard drug. Aqueous extract of M. koenigii Linn. significantly and dose-dependently reduced the number of acetic acid-induced writhing and significantly increased the latency of paw licking in hot plate method. Statistical analysis was carried out by one-way ANOVA, followed by Turkey's test.

Conclusion: Aqueous extract of M. koenigii Linn. possesses both anti-inflammatory and analgesic activity in a dose-dependent manner.

Key words: Murraya koenigii; Anti-inflammatory; Analgesic; Carrageenan; Paw Edema

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Pubmed Style

Singh A, Singh A, Chouhan O, Tandi GP, Dua M, Gehlot A. Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.. Natl J Physiol Pharm Pharmacol. 2016; 6(4): 286-290. doi:10.5455/njppp.2016.6.09122015123

Web Style

Singh A, Singh A, Chouhan O, Tandi GP, Dua M, Gehlot A. Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.. https://www.njppp.com/?mno=210380 [Access: November 02, 2025]. doi:10.5455/njppp.2016.6.09122015123

AMA (American Medical Association) Style

Singh A, Singh A, Chouhan O, Tandi GP, Dua M, Gehlot A. Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.. Natl J Physiol Pharm Pharmacol. 2016; 6(4): 286-290. doi:10.5455/njppp.2016.6.09122015123

Vancouver/ICMJE Style

Singh A, Singh A, Chouhan O, Tandi GP, Dua M, Gehlot A. Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.. Natl J Physiol Pharm Pharmacol. (2016), [cited November 02, 2025]; 6(4): 286-290. doi:10.5455/njppp.2016.6.09122015123

Harvard Style

Singh, A., Singh, . A., Chouhan, . O., Tandi, . G. P., Dua, . M. & Gehlot, . A. (2016) Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.. Natl J Physiol Pharm Pharmacol, 6 (4), 286-290. doi:10.5455/njppp.2016.6.09122015123

Turabian Style

Singh, Ateendra, Anamika Singh, Omi Chouhan, Gyan Prakash Tandi, Mitali Dua, and Anusuya Gehlot. 2016. Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.. National Journal of Physiology, Pharmacy and Pharmacology, 6 (4), 286-290. doi:10.5455/njppp.2016.6.09122015123

Chicago Style

Singh, Ateendra, Anamika Singh, Omi Chouhan, Gyan Prakash Tandi, Mitali Dua, and Anusuya Gehlot. "Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 286-290. doi:10.5455/njppp.2016.6.09122015123

MLA (The Modern Language Association) Style

Singh, Ateendra, Anamika Singh, Omi Chouhan, Gyan Prakash Tandi, Mitali Dua, and Anusuya Gehlot. "Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.." National Journal of Physiology, Pharmacy and Pharmacology 6.4 (2016), 286-290. Print. doi:10.5455/njppp.2016.6.09122015123

APA (American Psychological Association) Style

Singh, A., Singh, . A., Chouhan, . O., Tandi, . G. P., Dua, . M. & Gehlot, . A. (2016) Anti-inflammatory and analgesic activity of aqueous extracts of dried leaves of Murraya koenigii Linn.. National Journal of Physiology, Pharmacy and Pharmacology, 6 (4), 286-290. doi:10.5455/njppp.2016.6.09122015123

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